設計與合成... 新穎人類粒線體 NAD(P)+ 依賴型蘋果酸酶2抑制劑用於癌症治療 (Design and Synthesis of Novel Human Mitochondrial NAD(P)+-Dependent Malic Enzyme 2 (ME2) Inhibitors for Cancer Therapies)more

設計與合成新穎人類粒線體 NAD(P)+ 依賴型蘋果酸酶2抑制劑用於癌症治療 (Design and Synthesis of Novel Human Mitochondrial NAD(P)+-Dependent Malic Enzyme 2 (ME2) Inhibitors for Cancer Therapies)

(±)-P... elseneeriol-1和-2的全合成 (Total synthesis of (±)-Pelseneeriol-1 and -2)more

(±)-Pelseneeriol-1和-2的全合成 (Total synthesis of (±)-Pelseneeriol-1 and -2)

天然物 C... umbiasins 全合成：建構 Cumbiane 四環骨架中C3、C6及C7之立體化學 (Total Synthesis of Cumbiasins：Construction of the C3, C6 and C7 Stereocenters in the Cumbiane skeleton)more

天然物 Cumbiasins 全合成：建構 Cumbiane 四環骨架中C3、C6及C7之立體化學 (Total Synthesis of Cumbiasins：Construction of the C3, C6 and C7 Stereocenters in the Cumbiane skeleton)

壹、 設計... 與合成氟喹諾酮類衍生物為泛連接I型蛋白抑制劑應用於結腸炎治療之研究 貳、 改善組織蛋白酶S抑制劑之水溶性應用於與神經相關之疾病探討 (I. Design and Synthesis of Fluoroquinolone Derivatives as Pannexin 1 Inhibitors for the Treatment of Colitis II. Improving the Water Solubility of Cathepsin S Inhibitors for Applications in Neurological Disorders)more

壹、 設計與合成氟喹諾酮類衍生物為泛連接I型蛋白抑制劑應用於結腸炎治療之研究 貳、 改善組織蛋白酶S抑制劑之水溶性應用於與神經相關之疾病探討 (I. Design and Synthesis of Fluoroquinolone Derivatives as Pannexin 1 Inhibitors for the Treatment of Colitis II. Improving the Water Solubility of Cathepsin S Inhibitors for Applications in Neurological Disorders)

臺美藥品專... 利連結制度下專利迴避設計策略之比較研究—以臺灣學名藥廠涉入案例為基礎 (Comparative Analysis of Design-Around Strategies Under the Taiwan–U.S. Drug Patent Linkage Systems: Case Studies of Taiwanese Generic Drug Firms)more

臺美藥品專利連結制度下專利迴避設計策略之比較研究—以臺灣學名藥廠涉入案例為基礎 (Comparative Analysis of Design-Around Strategies Under the Taiwan–U.S. Drug Patent Linkage Systems: Case Studies of Taiwanese Generic Drug Firms)

解析美國新... 藥上市途徑及決策機制：眼用製劑的應用與挑戰 (A Study on U.S. New Drug Approval Pathways and Decision Mechanisms: Applications and Challenges in Ophthalmic Products)more

解析美國新藥上市途徑及決策機制：眼用製劑的應用與挑戰 (A Study on U.S. New Drug Approval Pathways and Decision Mechanisms: Applications and Challenges in Ophthalmic Products)

美國止痛藥... 品法規調整下對小分子藥品開發影響之研析 (Exploring the Impact of U.S. Regulatory Adjustments on Small-Molecule Drugs for Pain Management)more

美國止痛藥品法規調整下對小分子藥品開發影響之研析 (Exploring the Impact of U.S. Regulatory Adjustments on Small-Molecule Drugs for Pain Management)

天然物 (... ±)-Cumbiasins 之全合成研究 (Synthetic Study toward The Total Syntheses of (±)-Cumbiasins)more

天然物 (±)-Cumbiasins 之全合成研究 (Synthetic Study toward The Total Syntheses of (±)-Cumbiasins)

設計與開發... DYRK1A抑制劑作為治療阿茲海默症的潛在藥物 (Design and Discovery of DYRK1A Inhibitors as Potential Therapeutics for Alzheimer’s Disease)more

設計與開發DYRK1A抑制劑作為治療阿茲海默症的潛在藥物 (Design and Discovery of DYRK1A Inhibitors as Potential Therapeutics for Alzheimer’s Disease)

具腦滲透性... 以及選擇性CSF1R抑制劑的設計與合成 : 以循理性方式削弱對c-KIT抑制活性之研究 (Design and synthesis of brain-penetrant and selective CSF1R inhibitors: A rational approach to diminishing the inhibitory activity against c-KIT)more

具腦滲透性以及選擇性CSF1R抑制劑的設計與合成 : 以循理性方式削弱對c-KIT抑制活性之研究 (Design and synthesis of brain-penetrant and selective CSF1R inhibitors: A rational approach to diminishing the inhibitory activity against c-KIT)

設計與合成... 盤狀結構域受體 1 激酶抑制劑以應用於治療多形性膠質母細胞瘤之研究 (Design and Synthesis of DDR1 Kinase Inhibitors for the Treatment of Glioblastoma Multiforme)more

設計與合成盤狀結構域受體 1 激酶抑制劑以應用於治療多形性膠質母細胞瘤之研究 (Design and Synthesis of DDR1 Kinase Inhibitors for the Treatment of Glioblastoma Multiforme)

設計與合成... CK1ε抑制劑用於多形性膠質母細胞瘤治療之構效關係研究 (Design and synthesis of selective CK1ε inhibitors for the treatment of glioblastoma multiforme)more

設計與合成CK1ε抑制劑用於多形性膠質母細胞瘤治療之構效關係研究 (Design and synthesis of selective CK1ε inhibitors for the treatment of glioblastoma multiforme)

設計與合成... 7-胺基喹唑啉化合物為口服選擇性CSF1R激酶抑制劑應用於癌症免疫治療之研究 (Design and Synthesis of 7-Aminoquinazolines as Orally Available and Selective CSF1R Kinase Inhibitors for Cancer Immunotherapy)more

設計與合成7-胺基喹唑啉化合物為口服選擇性CSF1R激酶抑制劑應用於癌症免疫治療之研究 (Design and Synthesis of 7-Aminoquinazolines as Orally Available and Selective CSF1R Kinase Inhibitors for Cancer Immunotherapy)

癌症免疫C... SF1R抑制劑先導藥物最佳化:連接體與末端側鏈修飾和平行合成平台建立 (Lead Optimization of Immunomodulatory CSF1R Inhibitor : Linker and Terminal Moiety Modification and Parallel Synthesis Platform Establishment)more

癌症免疫CSF1R抑制劑先導藥物最佳化:連接體與末端側鏈修飾和平行合成平台建立 (Lead Optimization of Immunomodulatory CSF1R Inhibitor : Linker and Terminal Moiety Modification and Parallel Synthesis Platform Establishment)

合成KIF... 2C抑制劑用於三陰性乳癌治療之構效關係研究 (Discovery of KIF2C Inhibitor as Potential Triple Negative Breast Cancer Treatment)more

合成KIF2C抑制劑用於三陰性乳癌治療之構效關係研究 (Discovery of KIF2C Inhibitor as Potential Triple Negative Breast Cancer Treatment)

壹、設計與... 合成喹唑啉衍生物為原肌球蛋白受體激酶抑制劑之研究 貳、天然物 (±)-7-epi-Teucrenone 及 (±)-Oxyphyllanene A 之全合成研究 (I. From Multiple to Selective: Design and Synthesis of Quinazoline-based Derivatives as Tropomyosin Receptor Kinase Inhibitors II. Total Synthesis of (±)-7-epi-Teucrenone and (±)-Oxyphyllanene A)more

壹、設計與合成喹唑啉衍生物為原肌球蛋白受體激酶抑制劑之研究 貳、天然物 (±)-7-epi-Teucrenone 及 (±)-Oxyphyllanene A 之全合成研究 (I. From Multiple to Selective: Design and Synthesis of Quinazoline-based Derivatives as Tropomyosin Receptor Kinase Inhibitors II. Total Synthesis of (±)-7-epi-Teucrenone and (±)-Oxyphyllanene A)

環張力對雙... 環[2.2.2]辛烯酮系統上醯基自由基環化反應的影響之研究 (Effect of Ring Strain on Acyl Radical Cyclization of Bicyclo[2.2.2]octenone System)more

環張力對雙環[2.2.2]辛烯酮系統上醯基自由基環化反應的影響之研究 (Effect of Ring Strain on Acyl Radical Cyclization of Bicyclo[2.2.2]octenone System)

醯基自由基... 環化反應應用於異扭曲烷骨架之合成 (Study the Application of Acyl Radical Cyclization for Constructing Isotwistance Skeleton)more

醯基自由基環化反應應用於異扭曲烷骨架之合成 (Study the Application of Acyl Radical Cyclization for Constructing Isotwistance Skeleton)

天然物 (... ±)-Isopalhinine A、(±)-Palhinine A 與 (±)-Palhinine D 的仿生合成 (Biomimetic Syntheses of (±)-Isopalhinine A, (±)-Palhinine A and (±)-Palhinine D)more

天然物 (±)-Isopalhinine A、(±)-Palhinine A 與 (±)-Palhinine D 的仿生合成 (Biomimetic Syntheses of (±)-Isopalhinine A, (±)-Palhinine A and (±)-Palhinine D)

EGFR與... c-Met雙重激酶抑制劑及DBPR104磷酸前驅物之合成研究 (The Developments of Dual EGFR and c-Met Kinase Inhibitors and DBPR104 Phosphate Prodrugs)more

EGFR與c-Met雙重激酶抑制劑及DBPR104磷酸前驅物之合成研究 (The Developments of Dual EGFR and c-Met Kinase Inhibitors and DBPR104 Phosphate Prodrugs)

設計與開發... 第三代 EGFR 酪胺酸激酶抑制劑 (Design and Discovery of 3rd Generation EGFR Tyrosine Kinase Inhibitors)more

設計與開發第三代 EGFR 酪胺酸激酶抑制劑 (Design and Discovery of 3rd Generation EGFR Tyrosine Kinase Inhibitors)

開發新穎抗... 癌藥物 DBPR104 之前驅藥物：設計、合成與藥物性質評估 (Design, Synthesis, and Drug-property Evaluation of Anticancer DBPR104 Prodrugs)more

開發新穎抗癌藥物 DBPR104 之前驅藥物：設計、合成與藥物性質評估 (Design, Synthesis, and Drug-property Evaluation of Anticancer DBPR104 Prodrugs)