政府計畫(GRB),建議「依年度遞減排序」,以查看最新的研究方向。
畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
---|---|---|---|---|
關鍵字 | ||||
113 | 反轉基因法... 反轉基因法於多種腸病毒疫苗之發展與應用 (Multi-Species Enterovirus Vaccine Development Using Reverse Genetics Systems) | NTHU | 博 | 暫無口試日期 |
腸病毒(Enterovirus)、雙價疫苗(Bivalent vaccine)、反轉基因法(Reverse Genetics)、無血清HEK293A細胞懸浮培養(Serum-free HEK293A suspension culture)、去活化疫苗(inactivated vaccine) 腸病毒(E... | ||||
112 | 以三價神經... 以三價神經胺酸酶抗原及其保守HCA2序列作為廣效型鼻噴流感疫苗之研究 (Trivalent Neuraminidase antigens with the universally conserved HCA2 sequence as a broad-spectrum intranasal influenza vaccine) | NTHU NDLTD | 碩 | 2.00 |
流感疫苗(influenza vaccine)、鼻噴免疫(intranasal immunization)、重組神經胺酸酶(recombinant neuraminidase)、廣效保守序列(broadly conserved sequence) 流感疫苗(... | ||||
112 | 探討克沙奇... 探討克沙奇病毒A16型結構蛋白的位點替換對病毒特性之影響 (Site Substitution of Coxsackievirus A16 Structural Proteins Affects the Virus Characteristics) | NTHU NDLTD | 碩 | 1.99 |
腸病毒(Enterovirus)、克沙奇病毒A16型(CVA16)、感染性克隆(Infectious clone)、衣殼蛋白突變(Mutations in capsid protein)、手足口症(Hand, foot, and mouth disease (HFMD)) 腸病毒(E... | ||||
112 | 建構以重組... 建構以重組腺相關病毒載體系統表現流感神經胺酸酶發展流感疫苗 (Construction of a Recombinant Adeno-Associated Virus Vector System to Express Neuraminidase and Develop Influenza Vaccines) | NTHU NDLTD | 碩 | 1.99 |
神經胺酸酶(Neuraminidase)、腺相關病毒(Adeno-Associated Virus)、流感病毒(Influenza virus) 神經胺酸酶... | ||||
112 | 第二b型忌... 第二b型忌熱型腸毒素作為黏膜佐劑增強保護性免疫對抗H5N1禽流感病毒 (Type IIb Heat Labile Enterotoxin B Subunit as a Mucosal Adjuvant to Enhance Protective Immunity against H5N1 Avian Influenza Viruses) | NTHU NDLTD | 碩逕博 | 10.50 |
大腸桿菌第二b 型忌熱型腸毒素 之B 次單元(LTIIb-B5)、黏膜佐劑(mucosal adjuvant)、IL-17A(IL-17A)、H5N1(H5N1) 大腸桿菌第... | ||||
111 | 結合大腸桿... 結合大腸桿菌忌熱型腸毒素第二B型A次單元與神經胺酸酶融合蛋白之小鼠噴鼻式疫苗開發 (Intranasal immunization with Type IIb E.coli Heat-Labile Enterotoxin A Subunit and Neuraminidase fusion protein for Influenza vaccine development) | NTHU NDLTD | 碩 | 1.98 |
神經胺酸脢(Neuraminidase)、鼻噴免疫(Mucosal immunization)、大腸桿菌忌熱型腸毒素(Type IIb E.coli Heat-Labile Enterotoxin)、流感疫苗(influenza vaccine) 神經胺酸脢... | ||||
111 | 鼻噴免疫重... 鼻噴免疫重組神經胺酸酶蛋白對抗A型與B型流感病毒感染 (Intranasal immunization with recombinant neuraminidase proteins against influenza A and B virus infection) | NTHU NDLTD | 碩 | 1.98 |
流感(influenza)、疫苗(vaccine)、神經胺酸酶(neuraminidase)、黏膜(mucosa)、佐劑(adjuvant) 流感(in... | ||||
111 | 開發高效能... 開發高效能次單位疫苗對抗新型冠狀病毒感染之研究 (Studies of Developing High Efficacy Subunit Vaccine Against SARS-CoV-2 Infection) | NTHU NDLTD | 博 | 6.89 |
新型冠狀病毒(SARS-CoV-2)、棘蛋白三聚體(Trimeric spike)、蛋白質次單位疫苗(Protein subunit vaccine)、Th1導向的免疫反應(Th1-biased response)、氫氧化鋁(squalene-in-water emulsion)、角鯊烯乳化佐劑(DNA+protein combuned vaccine) 新型冠狀病... | ||||
110 | 結合新冠肺... 結合新冠肺炎及流感似病毒顆粒疫苗之開發 (Development of COVID-19 and Influenza Combination VLP Vaccine) | NTHU NDLTD | 碩 | 1.99 |
似病毒顆粒(VLP)、新型冠狀病毒(SARS-CoV-2)、流感病毒(Influenza)、鞭毛蛋白(Hemagglutinin) 似病毒顆粒... | ||||
110 | 醣遮蔽於流... 醣遮蔽於流感病毒神經胺酸酶引起廣效性神經酸胺酶抑制抗體 (Glycan masking of Neuraminidase antigen elicited broadly reactive neuraminidase inhibiting antibodies against influenza viruses) | NTHU NDLTD | 碩 | 1.99 |
流感(influenza viruses)、神經胺酸酶(Neuraminidase)、醣遮蔽(Glycan masking)、廣效型抑制抗體(broadly reactive neuraminidase inhibiting antibodies) 流感(in... | ||||
109 | 以去醣化與... 以去醣化與醣遮蔽棘蛋白抗原開發次世代新冠疫苗 (Use of Deglycaned and Glycan-Masked Spike Proteins for Next-Generation COVID-19 Vaccine Development) | NTHU NDLTD | 碩 | 2.22 |
新型冠狀病毒(COVID-19)、新冠肺炎疫苗(SARS-CoV-2)、嚴重特殊傳染性肺炎(SARS-CoV-2 vaccine) 新型冠狀病... | ||||
109 | 肺炎黴漿菌... 肺炎黴漿菌感染分子分型分析與檢測試劑研發 (Development of serological test methods and molecular typing of Mycoplasma pneumoniae) | NTHU NDLTD | 碩 | 2.08 |
肺炎黴漿菌(Mycoplasma pneumoniae)、MLVA 分子分型分析(Multiple-locus variable-number tandem-repeat analysis (MLVA))、P1 附著蛋白(P1 adhesion protein)、血清檢測(Serological test)、免疫(Immunization) 肺炎黴漿菌... | ||||
109 | 醣遮蔽棘蛋... 醣遮蔽棘蛋白技術開發第三代新冠肺炎疫苗抗原 (Glycan-Masking the Spike Antigen of SARS-CoV-2 for Third-Generation Vaccine COVID-19 Vaccine Development) | NTHU NDLTD | 碩 | 3.07 |
疫苗(Glycan-Masking)、新冠肺炎(COVID-19)、醣遮蔽(SARS-CoV-2)、棘蛋白(Vaccine)、腺病毒載體(adeno virus)、次世代疫苗開發(Spike protein) 疫苗(Gl... | ||||
109 | 以重組血凝... 以重組血凝素與神經胺酸酶蛋白噴鼻免疫開發H7N9禽流感疫苗 (Intranasal Immunizations with Recombinant Neuraminidase and Hemagglutinin Proteins for H7N9 Avian Influenza Vaccine Development) | NTHU NDLTD | 碩 | 2.07 |
H7N9禽流感(H7N9 avian influenza)、噴鼻免疫(intranasal immunization)、血凝素(hemagglutinin)、神經胺酸脢(neuraminidase)、疫苗(vaccine) H7N9禽... | ||||
109 | 以新型冠狀... 以新型冠狀病毒棘突蛋白受體結合區融合大腸桿菌第二型b型忌熱型腸毒素A次單元開發鼻噴型新冠肺炎黏膜疫苗 (Intranasal immunization with the receptor-binding domain of SARS-CoV-2 spike protein fused with the type IIb E. coli heat-labile enterotoxin A subunit for COVID-19 mucosal vaccine development) | NTHU NDLTD | 碩 | 2.07 |
新型冠狀病毒(SARS-CoV-2)、新冠肺炎(COVID-19)、棘突蛋白(spike protein)、受體結合區(receptor-binding domain)、黏膜疫苗(mucosal vaccine)、鼻內免疫(Intranasal immunization)、大腸桿菌第二型b型忌熱型腸毒素(type IIb E. coli heat-labile enterotoxin)、腸毒素A次單元(enterotoxin A subunit) 新型冠狀病... | ||||
109 | 流感病毒神... 流感病毒神經胺酸酶370 loop突變對於其酵素活性、血凝素與神經胺酸酶平衡、小鼠毒性、以及其去活化病毒疫苗之免疫反應研究 (Characterization of the influenza virus neuraminidase 370-loop mutations for NA enzyme activity, HA-NA balancing, mouse virulence, and inactivated virus immunogenicity.) | NTHU NDLTD | 博 | 6.93 |
流感病毒(influenza virus)、神經胺酸酶(neuraminidase)、疫苗(vaccine) 流感病毒(... | ||||
108 | 含機能性脂... 含機能性脂質之奈米乳液對於樹突狀細胞的免疫調節作用 (Immunomodulatory Effect of Nanoemulsions Based on Functional Hydrocarbons on Dendritic Cells) | NTHU NDLTD | 碩 | 2.88 |
奈米乳液(nanoemulsion)、機能性脂質(hydrocarbon)、樹突狀細胞(functional hydrocarbon)、免疫調節(ω-3 fatty acid)、ω-3脂肪酸(ω-6 fatty acid)、ω-6脂肪酸(dendritic cell) 奈米乳液(... | ||||
107 | 茲卡病毒膜... 茲卡病毒膜蛋白第三區域與鞭毛素融合蛋白分子工程應用於噴鼻式疫苗開發 (Molecular engineering of flagellin fusion with Zika virus envelope protein domain III for intranasal vaccine development) | NTHU NDLTD | 碩(提早入學) | 2.47 |
茲卡病毒(Zika Virus)、鞭毛蛋白(Vaccine)、疫苗(Flagellin fusion) 茲卡病毒(... | ||||
107 | 亞洲眼鏡蛇... 亞洲眼鏡蛇毒之蛋白質體分析與新型抗蛇毒血清研發 (Study on Venom Proteome of Asiatic Cobras and its Application on Novel Antivenom Development) | NTHU NDLTD | 博 | 6.66 |
眼鏡蛇毒(Cobra venom)、蛇毒蛋白質體學(Venom proteome)、廣效型抗蛇毒血清(Broad-spectrum antivenom)、質譜分析(Mass spectrometry) 眼鏡蛇毒(... | ||||
106 | A型流感神... A型流感神經胺酸酶之唾液酸結合區與其誘發神經胺酸酶抑制性抗體之研究 (The secondary sialic acid binding site of influenza A viruses on virus neuraminidase and the elicitation of neuraminidase-inhibiting antibodies) | NTHU NDLTD | 碩 | 1.99 |
流感病毒(influenza virus)、神經胺酸酶(neuraminidase)、神經胺酸酶抑制性抗體(neuraminidase-inhibiting antibody)、唾液酸結合區(secondary sialic acid binding site) 流感病毒(... | ||||
106 | 設計具多重... 設計具多重弗林切位點之重組茲卡類病毒顆粒疫苗 (Recombinant Zika virus-like particles containing a multiple furin cleavage site for vaccine design) | NTHU NDLTD | 碩 | 1.98 |
茲卡病毒(Zika virus)、疫苗(vaccine)、類病毒顆粒(virus-like particle) 茲卡病毒(... | ||||
106 | 茲卡病毒套... 茲卡病毒套膜第三區域重組蛋白與黏膜佐劑之疫苗研發 (Zika virus envelope domain III recombinant proteins formulated with mucosal adjuvants for vaccine development) | NTHU NDLTD | 碩 | 1.98 |
茲卡病毒(ZIKV)、黏膜疫苗(mucosal vaccine)、疫苗佐劑(adjuvant)、靈芝多醣體(PS-G) 茲卡病毒(... | ||||
106 | 擠壓程序對... 擠壓程序對於乳液粒子之粒徑分佈影響以及鼻黏膜疫苗遞送之研究 (A study on the effects of the extrusion process on the size distribution of emulsified particles and the intranasal delivery of vaccine) | NTHU NDLTD | 碩 | 2.44 |
乳液(emulsion)、疫苗佐劑(vaccine adjuvant)、鼻黏膜疫苗遞送(intranasal delivery of vaccine)、疫苗(vaccine吳夙欽 博士(Suh-Chin Wu) 乳液(em... | ||||
105 | 結合APR... 結合APRIL或BAFF之高免疫性多價流感類病毒顆粒疫苗 (High immunogenic influenza virus-like particles containing APRIL or BAFF for multi-subtype vaccine development) | NTHU NDLTD | 碩 | 1.98 |
流感(Influenza)、疫苗(vaccine)、類病毒顆粒(VLP) 流感(In... | ||||
105 | 腺病毒載體... 腺病毒載體表現茲卡病毒套膜蛋白之疫苗研發 (Vaccine development of Zika envelope protein expressed by adenovirus-vector) | NTHU NDLTD | 碩 | 1.98 |
茲卡病毒(Zika virus)、腺病毒載體(ZIKV)、茲卡套膜蛋白(ZIKV envelope protein)、疫苗(adenovirus-vector)、疫苗研發(vaccine) 茲卡病毒(... | ||||
105 | 利用大腸桿... 利用大腸桿菌暨熱型腸毒素融合蛋白用於禽流感次單位疫苗的開發 (Application of recombinant fusion protein vaccine against influenza virus) | NTHU NDLTD | 碩 | 1.98 |
忌熱型腸毒素(vaccine)、疫苗(influenza)、禽流感(heat-labile enterotoxin) 忌熱型腸毒... | ||||
105 | 以H5N1... 以H5N1禽流感神經胺酸酶重組蛋白免疫誘導交叉性神經胺酸酶抑制性抗體之研究 (Mapping cross-reactive epitopes for NA inhibiting antibodies elicited by H5N1 NA protein immunizations) | NTHU NDLTD | 碩 | 1.98 |
H5N1禽流感(NA inhibiting antibodies)、神經胺酸酶(H5N1 NA protein immunizations)、流感病毒(undefined) H5N1禽... | ||||
104 | 結合醣遮蔽... 結合醣遮蔽與去醣基化策略應用於創新型血凝素流感疫苗之設計 (A Combination of Glycan Masking and Glycan Unmasking Strategies as A Novel Influenza Hemagglutinin Vaccine Design) | NTHU NDLTD | 碩 | 暫無口試日期 |
流行性感冒(Influenza Viurs)、醣遮蔽與去醣基化(Glycan masking/unmasking) 流行性感冒... | ||||
104 | 以神經胺酸... 以神經胺酸酶重組蛋白免疫引發交叉性抑制抗體之抗原表位研究 (Dissecting cross-reactive epitopes for the induction of NA-inhibiting antibodies via recombinant NA protein immunizations) | NTHU NDLTD | 碩 | 暫無口試日期 |
A型流感病毒(Influenza A viruses)、神經胺酸酶(Neuraminidase)、神經胺酸酶抑制抗體(Neuraminidase-inhibiting antibodies)、交叉性抑制抗體(cross-reactive antibodies) A型流感病... | ||||
104 | Devel... Development of immunofocusing virus-like particles as broadly protective influenza vaccines (以免疫聚焦性類病毒顆粒研製廣效性流感疫苗) | NTHU NDLTD | 碩 | 暫無口試日期 |
流行性感冒(Influenza A virus)、類病毒顆粒(Virus-like particle)、分子佐劑(molecular adjuvant) 流行性感冒... | ||||
103 | 開發重組H... 開發重組H7N9血凝素禽流感黏膜疫苗 (Studies of recombinant HA proteins with different adjuvants for avian influenza H7N9 mucosal vaccine development) | NTHU NDLTD | 碩 | 暫無口試日期 |
黏膜疫苗(mucosal vaccine)、H7N9(H7N9) 黏膜疫苗(... | ||||
103 | 利用醣遮蔽... 利用醣遮蔽與去醣基化血凝素之類病毒顆粒引發H5N1禽流感廣效性中和抗體 (Influenza virus-like particles by glycan masking and unmasking of hemagglutinin antigens to induce broadly neutralizing antibodies against H5N1 avian influenza viruses) | NTHU NDLTD | 碩 | 暫無口試日期 |
禽流感(avian influenza)、類病毒顆粒(virus-like particle)、H5N1(H5N1)、疫苗(vaccine) 禽流感(a... | ||||
102 | 以減毒活病... 以減毒活病毒、腺病毒載體及套膜蛋白第三區域融合蛋白 作為第二、四型登革疫苗之免疫性研究 (Immunization studies for dengue serotype 2/4 vaccines using live-attenuated virus, adenoviral vector and envelope domain III fusion protein) | NTHU NDLTD | 碩 | 暫無口試日期 |
減毒活病毒(live-attenuated virus)、腺病毒載體(adenoviral vector)、套膜蛋白(envelope protein)、融合蛋白(fusion protein)、登革疫苗(dengue vaccine) 減毒活病毒... | ||||
102 | 新穎性神經... 新穎性神經氨酸酶突變蛋白以提升異源型流感病毒之神經氨酸酶抑制性抗體與免疫保護力 (Novel Neuraminidase Mutants Proteins to Enhance Heterosubtypic NA-Inhibiting Antibodies and cross-protective immunity against influenza A virus) | NTHU NDLTD | 碩 | 暫無口試日期 |
神經胺酸酶(Neuraminidase)、A型流感病毒(Influenza A virus) 神經胺酸酶... | ||||
102 | H7N9禽... H7N9禽流感血凝素之 重組蛋白、腺病毒載體與類病毒顆粒之 免疫性研究 (Immunogenicity of recombinant protein, adenovirus vector and virus-like particles of the avian-origin influenza H7N9 virus hemagglutinin) | NTHU NDLTD | 碩 | 暫無口試日期 |
禽流感(influenza)、H7N9(Hemagglutinin)、血凝素(vaccine)、疫苗(undefined) 禽流感(i... | ||||
101 | 利用禽流感... 利用禽流感H5N1及新興流感pH1N1之神經胺酸脢重組蛋白誘導神經胺酸脢抑制性抗體及保護性免疫力之研究 (Neuraminidase-inhibiting antibodies and protective immunity elicited by recombinant neuraminidase proteins of H5N1 and pH1N1 Influenza A Viruses) | NTHU NDLTD | 碩 | 暫無口試日期 |
禽流感(Avian flu)、新興流感 H1N1(Pandemic H1N1)、神經胺酸脢(Neuraminidase)、保護性免疫力(Protective immunity)、抗原漂變(Antigenic drift) 禽流感(A... | ||||
101 | 利用腺病毒... 利用腺病毒載體及第三區域套膜蛋白融合重組鞭毛蛋白進行prime-boost免疫法研發四價登革熱疫苗 (Prime-boost immunization using adenovirus vector and envelope domain III protein fused with flagellin for tetravalent dengue vaccine development) | NTHU NDLTD | 碩 | 暫無口試日期 |
腺病毒(prime-boost immunization)、鞭毛蛋白(dengue virus)、登革熱(flagellin)、第三區域套膜蛋白(EDIII) 腺病毒(p... | ||||
101 | 移除A型流... 移除A型流感病毒血凝素軀幹部N-linked醣基以誘發異型中和性抗體與交叉保護免疫性之研究 (Removal of N-linked glycan(s) in the stem region of influenza A virus hemagglutinin proteins to elicit heterosubtypic neutralizing antibodies and cross-protective immunity) | NTHU NDLTD | 碩 | 暫無口試日期 |
禽流感、血凝素、軀幹部、N-linked 醣基、中和性抗體 禽流感、血... | ||||
101 | 探討乳液配... 探討乳液配方的分散性質對於抗原遞送以及疫苗免疫生成性的影響 (A study on the dispersion properties of emulsion formulations affecting the antigen delivery and vaccine immunogenicity) | NTHU NDLTD | 碩 | 暫無口試日期 |
乳液、疫苗、疫苗佐劑 乳液、疫苗... |