政府計畫(GRB),建議「依年度遞減排序」,以查看最新的研究方向。
畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
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關鍵字 | ||||
112 | 轉錄因子P... 轉錄因子PsrA在綠膿桿菌PAO1中調控群體感應的作用 (Roles of transcriptional factor PsrA in the regulation of quorum sensing in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 博 | 8.00 |
綠膿桿菌(Pseudomonas aeruginosa)、群體感應(Quorum-sensing)、油酸(oleate)、PsrA(PsrA)、LasR(LasR)、LipA(LipA) 綠膿桿菌(... | ||||
112 | 利用ε聚賴... 利用ε聚賴氨酸增強抗生素活性和改善絲素蛋白水凝膠的特性 (Utilization of epsilon-poly-L-lysine to enhance the antimicrobial activities of antibiotics and improve the properties of silk fibroin hydrogel) | NTHU NDLTD | 博 | 7.10 |
使用ε-聚賴氨酸(Epsilon-poly-L-lysine)、絲素蛋白(Silk fibroin) 使用ε-聚... | ||||
111 | 探討成纖維... 探討成纖維細胞生長因子-2促進細胞生長之最佳形式以及不同添加劑對其蛋白穩定性之影響 (Investigation of the effects of different forms of fibroblast growth factor 2 on cell growth and various excipients on the protein stability) | NTHU NDLTD | 碩 | 1.98 |
成纖維細胞生長因子-2(Fibroblast growth factor-2 (FGF-2))、蛋白質療法(Protein therapy)、DNA 療法(DNA therapy)、mRNA 療法(mRNA therapy)、藥物賦形劑(Pharmaceutical excipients) 成纖維細胞... | ||||
111 | 選殖與鑑定... 選殖與鑑定體外轉錄訊息RNA用酵素 (Cloning and characterization of mRNA in vitro transcription enzymes) | NTHU NDLTD | 碩 | 3.34 |
重組 T7 RNA 聚合酶(recombinant T7 RNA polymerase)、E. coli poly(A) 聚合酶(E. coli poly(A) polymerase)、非洲豬瘟病毒mRNA-加帽酶 (NPR868R)(African swine fever virus NP868R capping enzyme)、非放射性T7 RNA 聚合酶活性檢測方法(Radioisotope-free T7 RNA polymerase assay)、檢測鳥苷酸轉移酶活性的可視方法(visual detection method for guanylyltransferase assay) 重組 T7... | ||||
111 | 信使核糖核... 信使核糖核酸加帽之偵測 (A method for quantification of mRNA capping) | NTHU NDLTD | 碩 | 2.34 |
信使核糖核酸(5'capping)、5端加帽(mRNA)、偵測(detect)、定量(quantification) 信使核糖核... | ||||
110 | 整合型微流... 整合型微流體系統及關節液生物標誌物於自動化人工關節感染之檢測 (Automatic detection of multiple synovial fluid biomarkers for periprosthetic joint infection on an integrated microfluidic system) | NTHU NDLTD | 碩 | 1.99 |
人工關節感染(Periprosthetic joint infection)、C-反應蛋白(C-reactive protein)、α-防禦素-1(α-defensin-1)、微流體晶片(Microfluidics)、酵素免疫分析法(Enzyme-linked immunosorbent assay)、人工適體實驗(ELISA-like assay)、關節液(synovial fluid) 人工關節感... | ||||
109 | 家蠶絲質蛋... 家蠶絲質蛋白敷料共軛第一型類胰島素生長因子應用於藥物遞送及糖尿病傷口治療之研究 (An Insulin-Like Growth Factor-1 Conjugated Bombyx mori Silk Fibroin Dressing for Drug Delivery and Diabetic Wound Therapy) | NTHU NDLTD | 博 | 7.23 |
家蠶(Bombyx mori L)、蠶絲絲質蛋白(silkworm)、第一型類胰島素生長因子(insulin-like growth factor-1)、傷口癒合(wound healing)、敷料(wound dressing)、糖尿病(diabetes) 家蠶(Bo... | ||||
109 | 利用瓊脂糖... 利用瓊脂糖和海藻酸鹽微球封裝Streptomyces thermoautotrophicus的醯胺酶StAmiE以提升其效能與穩定性 (Encapsulation of Streptomyces thermoautotrophicus acrylamidase StAmiE in alginate and agarose microspheres to improve its efficiency and stability) | NTHU NDLTD | 碩 | 2.09 |
丙烯醯胺(acrylamide)、丙烯醯胺酶(acrylamidase)、嗜熱自養鏈黴菌(Streptomyces thermoautotrophicus)、海藻酸鹽(alginate)、瓊脂糖(agarose)、奈米粒子(nanoparticle) 丙烯醯胺(... | ||||
109 | 固定於三維... 固定於三維骨支架的表皮生長因子對癌細胞增生和類腫瘤團塊形成 的影響 (The Effect of Epidermal Growth Factor Immobilized on 3D Bone Scaffold on Proliferation and Tumor-like Spheroid Formation of Cancer Cells) | NTHU NDLTD | 碩 | 2.05 |
乳癌(Breast cancer)、增生(proliferation)、支架(scaffold)、固定(Immobilization)、表皮生長因子(EGF)、細胞團(spheroid) 乳癌(Br... | ||||
108 | 白胺酸胺肽... 白胺酸胺肽酶 (PA2939)作為一種可增強綠膿桿菌B136-33與 PAO1的細胞毒性、黏附和侵入能力的毒性因子 (Leucine Aminopeptidase (PA2939) as a Virulence Factor Enhancing Cytotoxicity, Adhesion and Invasion of Pseudomonas aeruginosa B136-33 and PAO1) | NTHU NDLTD | 碩(外籍生) | 1.99 |
強綠膿桿菌(Pseudomonas aeruginosa)、白胺酸胺肽酶(P. aeruginosa)、的細胞毒性(Leucine aminopeptidase) 強綠膿桿菌... | ||||
108 | 利用明膠甲... 利用明膠甲基丙烯水凝膠覆蓋之透析膜建立空氣-液體介面之細胞培養系統 (Establishment of an Efficient Air-liquid Interface Culture System Using Dialysis Membranes Coated with Gelatin-methacrylamide) | NTHU NDLTD | 碩 | 1.99 |
空氣-液體介面細胞培養系統(Air-liquid interface culture system)、透析膜(dialysis membrane)、明膠甲基丙烯水凝膠(Gelatin-methacrylamide)、細胞層片(cell-sheet)、傷口癒合模型(wound-healing model)、腫瘤細胞遷移試驗(tumor cells migration test) 空氣-液體... | ||||
107 | 腸病毒非結... 腸病毒非結構蛋白之免疫性與針對EV71與CVA16之交叉保護效果 (The Immunogenicity of Non-Structure Protein Derived from Enterovirus Cross-Protects EV71 and CVA16 Infections) | NTHU NDLTD | 碩 | 2.58 |
腸病毒(enterovirus)、非結構蛋白(non-structure protein)、疫苗(vaccine)、佐劑(adjuvant) 腸病毒(e... | ||||
107 | 利用明膠甲... 利用明膠甲基丙烯水凝膠建立空氣-液體介面之細胞培養系統 (Establishment of an efficient air-liquid interface culture system using gelatin methacrylate hydrogel for biomedical applications) | NTHU NDLTD | 碩 | 2.00 |
細胞層片(cell sheet)、明膠(gelatin)、水凝膠(hydrogel)、空氣-液體介面(air-liquid interface) 細胞層片(... | ||||
107 | 綠膿桿菌外... 綠膿桿菌外毒素-A PE38於毒殺HEK293T細胞之應用 (Application of Cytotoxic Pseudomonas Exotoxin-A PE38 in HEK293T Killing) | NTHU NDLTD | 碩 | 2.00 |
綠膿桿菌(Pseudomonas)、外毒素A(Exotoxin-A)、細胞毒殺(PE38) 綠膿桿菌(... | ||||
107 | 轉錄調節因... 轉錄調節因子PsrA透過lasR調控綠膿桿菌PAO1之群體感應 (Transcriptional regulator PsrA regulates quorum sensing through lasR in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩 | 2.00 |
綠膿桿菌 PAO1(Pseudomonas aeruginosa PAO1)、群體感應(quorum sensing)、轉錄調節因子(Transcriptional regulator)、lasR(lasR)、PsrA(PsrA) 綠膿桿菌 ... | ||||
107 | 製造骨頭微... 製造骨頭微環境支架以研究骨轉移之乳癌 (Preparation of Scaffolds to Mimic Bone Microenvironment for Studying Bone Metastasized Breast Cancer) | NTHU NDLTD | 碩 | 2.00 |
表皮生長因子(Epidermal growth factor)、明膠(Gelatin)、羥磷灰石(Hydroxyapatite)、三維腫瘤微環境(3D bone microenvironment)、骨轉移(Bone metastasis) 表皮生長因... | ||||
106 | 克雷白氏肺... 克雷白氏肺炎桿菌之2,3-丁二醇代謝途徑的基因工程 (Metabolic Engineering of Butane-2,3-Diol Production Pathway in Klebsiella pneumoniae) | NTHU NDLTD | 碩 | 1.97 |
乙醯乙醇(acetoin)、2,3-丁二醇(butane 2,3-diol)、克雷白氏肺炎桿菌(Klebsiella pneumoniae)、基因工程(metabolic engineering) 乙醯乙醇(... | ||||
106 | 在克雷伯氏... 在克雷伯氏菌中操控生成2,3-丁二醇合成的途徑 (Manipulation of 2,3-butanediol pathway in Klebsiella pneumoniae) | NTHU NDLTD | 碩 | 1.97 |
2,3-丁二醇(2,3-butanediol)、克雷伯氏菌(Klebsiella pneumoniae)、2,3-丁二醇脫氫酶(2,3-butanediol dehydrogenase)、過量表現(overexpression)、薄層色層分析(Thin layer chromatography) 2,3-丁... | ||||
106 | 遠志與冬瓜... 遠志與冬瓜皮萃取物抑制3T3-L1脂肪細胞與高脂飼料誘發肥胖小鼠之脂肪累積並影響肝臟基因表現與腸道菌相分布 (Polygala tenuifolia and Benincasa hispida Extracts Inhibit Lipid Accumulation in 3T3-L1 Adipocytes and High-Fat Diet-Induced Obesity Mice and Affects Hepatic Transcriptome and Gut Microbiota Profiles) | NTHU NDLTD | 博 | 4.32 |
肥胖(Obesity)、遠志(Polygala tenuifolia)、冬瓜(Benincasa hispida)、腸道菌相(Gut microbiota) 肥胖(Ob... | ||||
105 | 綠膿桿菌P... 綠膿桿菌PAO1之轉錄因子PsrA於綠膿菌素生合成之調控 (Regulation of pyocyanin biosynthesis by transcriptional regulator PsrA in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩 | 1.98 |
綠膿桿菌(Pseudomonas aeruginosa)、綠膿菌素(pyocyanin)、轉錄因子 PsrA(transcriptional regulator PsrA) 綠膿桿菌(... | ||||
105 | 綠膿桿菌B... 綠膿桿菌B136-33之外分泌蛋白酶對於毒性與調節外分泌蛋白所扮演的角色 (Role of secreted proteases in virulence and proteolytic processing of secretome in Pseudomonas aeruginosa B136-33) | NTHU NDLTD | 碩 | 1.98 |
綠膿桿菌(Pseudomonas aeruginosa B136-33)、外分泌蛋白(secreted proteases) 綠膿桿菌(... | ||||
105 | 測試自動化... 測試自動化微流體系統篩選獲得之適體辨識細胞之專一性 (Evaluation of cell-recognizing specificity of aptamers selected by a microfluidic SELEX platform) | NTHU NDLTD | 碩 | 1.97 |
適體(Aptamer)、大腸癌(Colon cancer)、卵巢癌(Ovarian cancer)、自動化微流體系統(Automatically microfluidic system)、指數增幅型系統性配子演化法(SELEX)、癌症篩檢(Cancer screening) 適體(Ap... | ||||
105 | 利用絲質蛋... 利用絲質蛋白膜建立空氣-液體介面之細胞培養系統 (Establishment of air-liquid interface culture systems using silk fibroin films) | NTHU NDLTD | 碩 | 1.97 |
絲質蛋白(silk fibroin)、脫膠(degumming)、細胞生長情形(cell growth)、拉伸強度(tensile strength)、空氣-液體介面培養(air-liquid interface culture)、細菌入侵(bacterial invasion) 絲質蛋白(... | ||||
105 | 探討脂肪幹... 探討脂肪幹細胞以及BALB/c 3T3纖維母細胞在蠶絲布上的生長特性 (Investigation of the properties of adipose-derived stem cells and BALB/c 3T3 fibroblasts grown on silk fabric-based scaffolds) | NTHU NDLTD | 碩 | 2.87 |
疝氣(hernia)、蠶絲蛋白(fibroin)、脂肪幹細胞(adipose-derived stem cell)、纖維母細胞(fibroblast)、蠶絲布(silk fabric)、膠原蛋白(collagen) 疝氣(he... | ||||
104 | 探討鮑氏不... 探討鮑氏不動桿菌 ATCC 19606 之 PBP1a、PBP1b 以及 PBP3 在 sulbactam 抑制其生長時所扮演的角色 (Investigation of the Role of PBP1a, PBP1b and PBP3 on Antibacterial Mechanism of Sulbactam Against Acinetobacter baumannii ATCC 19606) | NTHU NDLTD | 碩 | 暫無口試日期 |
舒巴克坦(sulbactam)、鮑氏不動桿菌(Acinetobacter baumannii) 舒巴克坦(... | ||||
103 | 綠膿桿菌 ... 綠膿桿菌 B136-33 之LasA, LasB,與 PrpL 蛋白酶對胞外分泌蛋白質之調節與細菌生理之影響 (Modulation of Pseudomonas aeruginosa B136-33 secretome and the bacterial physiology by LasA, LasB and PrpL proteases) | NTHU NDLTD | 碩(外籍生) | 暫無口試日期 |
綠膿桿菌(Pseudoomonas aeruginosa)、外分泌蛋白質(Secretome)、蛋白酶(Proteases) 綠膿桿菌(... | ||||
103 | 探討脂肪幹... 探討脂肪幹細胞類球體膠原蛋白敷料促進傷口癒合的效果 (Investigation of the effects of a wound healing promoting matrix containing adipose-derived stem cell spheroids embedded in collagen) | NTHU NDLTD | 碩 | 暫無口試日期 |
傷口癒合(Wound healing)、脂肪幹細胞(Adipose-derived stem cell)、多細胞球體(Spheroids) 傷口癒合(... | ||||
102 | Therm... Thermus thermophilus HB8核苷酸激酶與核苷二磷酸激酶基因之選殖與應用於去氧核醣核苷三磷酸之合成 (Cloning of Deoxynucleoside Monophosphate Kinase and Deoxynucleoside Diphosphate Kinase Genes from Thermus thermophilus HB8 and Establishment of a New Enzymatic Method for Biosynthesis of Deoxynucleoside Triphosphates) | NTHU NDLTD | 碩 | 暫無口試日期 |
嗜熱菌HB8(Thermus thermophilus HB8)、核苷酸激酶(Deoxynucleoside Monophosphate Kinase)、核苷二磷酸激酶(Deoxynucleoside Diphosphate Kinase)、去氧核醣核苷三磷酸(Deoxynucleoside Triphosphate) 嗜熱菌HB... | ||||
102 | 綠膿桿菌P... 綠膿桿菌PAO1轉錄因子FliA於細菌群泳調控路徑中之作用 (Effects of FliA on Regulation of Swarming Motility of Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩(外籍生) | 暫無口試日期 |
綠膿桿菌(Pseudomonas aeruginosa)、轉錄因子FliA(FliA)、群泳(swarming)、鞭毛(flagellum)、環狀雙鳥嘌呤單磷酸(c-di-GMP)、磷酸二酯酶(phosphodiesterase) 綠膿桿菌(... | ||||
102 | 腺核苷酸對... 腺核苷酸對細胞移動、緊密連結與細胞毒性之影響 (Effects of Adenine Nucleotides on Cell Migration, Tight Junction Structure and Cytotoxicity) | NTHU NDLTD | 碩 | 暫無口試日期 |
腺苷酸激酶(Adenylate Kinase)、腺核苷酸(Adenine Nucleotides)、綠膿桿菌(Pseudomonas aeruginosa)、緊密連結(Tight Junction)、細胞毒性(Cytotoxicity)、細胞移動(Cell Migration) 腺苷酸激酶... | ||||
102 | 綠膿桿菌P... 綠膿桿菌PAO1轉錄因子RpoN與RpoN活化因子Sfa2對第二套第六型分泌系統之調控 (Co-regulation of H2-T6SS by sigma factor RpoN and RpoN activator Sfa2 in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩 | 暫無口試日期 |
綠膿桿菌(Pseudomonas aeruginosa)、轉錄因子 RpoN(sigma factor RpoN)、轉錄活化因子 Sfa2(RpoN activator)、第六型分泌系統(Type six secretion system) 綠膿桿菌(... | ||||
102 | 綠膿桿菌P... 綠膿桿菌PAO1氧化還原蛋白Azurin之生理功能及基因轉錄調控 (Physiological function and transcription regulation of Azurin, a redox protein in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩 | 暫無口試日期 |
Azurin、綠膿桿菌 Azuri... | ||||
102 | 利用表面電... 利用表面電漿共振儀研究固定式表皮生長因子於骨組織工程之應用 (A Surface Plasmon Resonance Study of Immobilized Epidermal Growth Factors for Bone Tissue Engineering Application) | NTHU NDLTD | 碩 | 暫無口試日期 |
表面電漿共振儀(Surface Plasmon Resonance)、表皮生長因子(Epidermal Growth Factor)、固定化(Immobilizatiom) 表面電漿共... | ||||
101 | 克雷白氏肺... 克雷白氏肺炎桿菌CG43全基因體解序、抗酸轉錄體分析與尿素酶基因群功能探討 (Whole Genome Sequencing, Transcriptome Analysis of Acid Response, and Urease Gene Cluster Characterization of Klebsiella pneumoniae CG43) | NTHU NDLTD | 碩 | 暫無口試日期 |
克雷白氏肺炎桿菌(Klebsiella pneumoniae)、基因體定序(genome sequence)、轉錄體(transcriptome)、尿素酶(urease) 克雷白氏肺... | ||||
101 | 開發以微載... 開發以微載體與微流體系統抓取、培養與觀察循環性癌細胞的簡易方法 (Development of a Simple Method for Capture, Propagation¸and Observation of Circulating Tumor Cells Using Microcarrier Beads and a Microfluidic Chip) | NTHU NDLTD | 碩 | 暫無口試日期 |
循環性癌細胞(Circulating tumor cell)、微載體(Microcarrier)、上皮細胞黏附分子(Epithelial cell adhesion molecule)、微流道(Microfluid)、晶片(Chip)、聚乙二醇二丙烯酸酯(PEGDA) 循環性癌細... | ||||
101 | 分析 PA... 分析 PA0262, PA1511 與 PA5266,三個可能與綠膿桿菌PAO1第六型分泌系統(二)相關的 VgrG 蛋白 (Characterization of PA0262, PA1511, and PA5266, Three Putative VgrGs Associated with the Type VI Secretion System-II in Pseudomonas aeruginosa PAO1) | NTHU NDLTD | 碩 | 暫無口試日期 |
綠膿桿菌(pseudomonas aeruginosa)、第六型分泌系統(type six secretion system)、VgrG(VgrG) 綠膿桿菌(... | ||||
101 | 多孔性氫氧... 多孔性氫氧基磷灰石作為抗憂鬱劑之載體以達到長期穩定藥物釋放系統 (Mesoporous Hydroxyapatite Particles as Olanzapine Carrier for Long-acting Delivery in Anti-depression Treatment) | NTHU NDLTD | 碩 | 暫無口試日期 |
憂鬱症(Depression)、氫氧基磷灰石(Hydroxyapatite)、長效型抗憂鬱藥劑(long acting delivery)、巨噬細胞(macrophage) 憂鬱症(D... | ||||
101 | 感溫性水膠... 感溫性水膠釋放抗氧化劑用於治療創傷性腦損傷之發展 (The Development of Thermosensitive Hydrogel for Anti-oxidant Release in Traumatic Brain Injury) | NTHU NDLTD | 碩 | 暫無口試日期 |
創傷性腦損傷(Traumatic brain injury)、感溫性水膠(Thermosensitive hydrogel)、藥物釋放(Drug releasing) 創傷性腦損... |