政府計畫(GRB),建議「依年度遞減排序」,以查看最新的研究方向。
畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
---|---|---|---|---|
關鍵字 | ||||
113 | 探討TCF... 探討TCF12–MALAT1在大腸直腸癌的聯合關係 (The TCF12–MALAT1 Alliance in Colorectal Cancer) | NTHU | 博 | 暫無口試日期 |
非編碼核糖核酸(no coding RNA)、轉錄因子 12(TCF12)、肺腺癌轉移相關之 轉錄物 1(MALAT1)、熱休克蛋白α(HSP90α)、大腸直腸癌(colorectal cancer)、微核糖核酸-145(miR-145) 非編碼核糖... | ||||
113 | 區分Omi... 區分Omicron變異株與其他SARS-CoV-2譜系的多重即時RT-qPCR之嶄新檢測策略開發 (Development of a new strategy of multiplex real-time RT-qPCR assay for differentiating Omicron variants from other SARS-CoV-2 lineages) | NTHU NDLTD | 碩逕博 | 10.33 |
SARS-CoV-2(SARS-CoV-2)、Omicron 變異株(Omicron variants)、多重 RT-qPCR(multiplex RT-qPCR)、擴增子競爭(amplicon-competition) SARS-... | ||||
112 | 粒線體Lo... 粒線體Lon蛋白誘導的腫瘤細胞外泌囊泡對於樹突細胞免疫抑制的角色 (The Role of Mitochondrial Lon-induced Extracellular Vesicles from Tumor in the Immunosuppression of Dendritic Cells) | NTHU NDLTD | 碩 | 2.00 |
Lon蛋白酶(Lon)、外泌囊泡(extracellular vesicles)、樹突細胞(dendritic cells)、腫瘤微環境(tumor microenvironment)、代謝體(metabolites) Lon蛋白... | ||||
112 | 下調slb... 下調slbo表現量於果蠅長壽及健康之研究 (Downregulation of slbo prolongs lifespan and enhances healthspan in Drosophila) | NTHU NDLTD | 碩 | 1.99 |
slbo(slbo)、果蠅(Drosophila)、長壽(longevity)、沉寂資訊調節者2(dSir2) slbo(... | ||||
112 | 咖啡酸苯乙... 咖啡酸苯乙酯結構類似物對前列腺癌細胞的抗癌活性研究 (Investigating the Anti-cancer Activity of Structure Analogues of Caffeic Acid Phenethyl Ester on Prostate Cancer Cells) | NTHU NDLTD | 碩 | 1.95 |
前列腺癌(Prostate Cancer)、去勢抵抗性前列腺癌(Castration-Resistant Prostate Cancer)、咖啡酸苯乙酯(Caffeic Acid Phenethyl Ester)、結構類似物(Structural Analogues)、雄激素受體(Androgen Receptor) 前列腺癌(... | ||||
112 | 探討Apo... 探討ApoD在前列腺癌中扮演的角色 (Investigate the role of ApoD in Prostate Cancer) | NTHU NDLTD | 碩 | 1.95 |
前列腺癌(ApoD)、攝護腺癌(undefined) 前列腺癌(... | ||||
112 | 探討Cts... 探討Ctss於早衰蛋白導致成年小鼠肌肉退化的功能性作用 (To investigate the functional role of Ctss in progerin-induced muscle degeneration in adult mice) | NTHU NDLTD | 碩 | 2.29 |
核纖層蛋白A(Lamin A)、早衰蛋白(Progerin)、組織蛋白酶S(Cathepsin S)、骨骼肌(Skeletal muscle)、纖維化(fibrosis) 核纖層蛋白... | ||||
111 | 研究B肝病... 研究B肝病毒 (HBV) 的性別差異和基因型C相關致癌性並開發抗肝癌的新療法 (Investigating Gender- and Genotype C-Associated Carcinogenicity of Hepatitis B Virus (HBV) and Developing Novel Therapeutics for Anti-Hepatocellular Carcinoma) | NTHU NDLTD | 碩 | 2.00 |
B型肝炎病毒(Hepatitis B virus)、基因型(HBV)、性別差異(genotype)、斑馬魚(Gender disparity)、肝細胞癌(zebrafish)、肝癌(hepatocellular carcinoma)、精準醫療(HCC)、藥物篩選(precision medicine) B型肝炎病... | ||||
111 | 降低out... 降低outsiders表現對於果蠅長壽及抗壓性之研究 (The study of reduced outsiders expression on longevity and stress resistance in Drosophila) | NTHU NDLTD | 碩 | 1.97 |
outsiders(outsiders)、果蠅(Drosophila)、長壽(longevity)、雙重壓力(double stress)、單磷酸腺苷活化蛋白質激酶(AMPK)、沉寂資訊調節者2(dSir2) outsi... | ||||
111 | 降低ras... 降低raspberry表現在果蠅壽命調控及壓力反應之研究 (The study of reduced raspberry expression in lifespan regulation and stress response in Drosophila) | NTHU NDLTD | 碩 | 1.97 |
果蠅(Drosophila)、raspberry(raspberry)、長壽(longevity)、雙重壓力(double stress)、AMPK(AMPK) 果蠅(Dr... | ||||
111 | 過度表現果... 過度表現果蠅溶酶體α-甘露糖苷酶V基因促進壽命及健康之研究 (Overexpression of Lysosomal α-mannosidase V promotes lifespan extension and healthspan in Drosophila) | NTHU NDLTD | 碩 | 1.97 |
溶酶體α-甘露糖苷酶V(Lysosomal α-mannosidase V)、果蠅(Drosophila)、抗老化(anti-aging)、細胞自噬(autophagy)、單磷酸腺苷活化蛋白質激酶(AMP-activated protein kinase) 溶酶體α-... | ||||
111 | 抑制Pfr... 抑制Pfrx通過減少果蠅中的胰島素以及TOR訊號傳遞路徑而改善壽命和健康狀況 (Inhibition of Pfrx improves lifespan and healthspan via reduced insulin and TOR signaling in Drosophila) | NTHU NDLTD | 碩 | 0.97 |
6-磷酸果糖激酶/果糖-2,6-雙磷酸酶(PFKFB (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase))、長壽(Longevity)、胰島素/胰島素樣生長因子訊號傳遞路徑(Insulin/Insulin-like growth factor (IGF-1) signaling)、雷帕黴素標靶蛋白訊息傳遞路徑(Target of rapamycin (TOR) pathway)、PFKFB3之小分子抑制劑PFK15(PFKFB3 inhibitor, PFK15)、黑腹果蠅(Drosophila) 6-磷酸果... | ||||
111 | 降低kin... 降低kin-19基因表達於特定時間點和組織促進秀麗隱桿線蟲壽命之調控 (Reduced kin-19 expression in specific time points and tissues promotes longevity in C. elegans) | NTHU NDLTD | 碩 | 0.97 |
酪蛋白激酶I亞型alpha(Casein kinase I alpha)、CKI 7(CKI 7)、雷帕黴素標靶蛋白(Target of rapamycin (TOR))、細胞自噬(autophagy)、單磷酸腺苷活化蛋白質激酶(AMP activated protein kinase (AMPK))、叉形頭轉錄因子(forkhead box transcription factor member of the class O (FOXO))、長壽(longevity)、線蟲(C. elegans) 酪蛋白激酶... | ||||
111 | 利用Mic... 利用Micro-Western Array找尋去勢後抗性攝護腺癌患者對澤珂抗藥性有關之蛋白質生物標的 (Applying Micro-Western Array to Identify Abiraterone-Resistance Related Protein Biomarkers in Castration-Resistance Prostate Cancer Patients) | NTHU NDLTD | 碩 | 1.92 |
攝護腺癌(Prostate Cancer)、去勢後抗性攝護腺癌(Castration-Resistance Prostate Cancer)、澤珂抗藥性(Abiraterone Resistance)、西方墨點微陣列(Micro-Western Array)、脂蛋白(Apolipoprotein) 攝護腺癌(... | ||||
111 | 於特定神經... 於特定神經元和時間點內降低核糖-5-磷酸異構酶A基因表達促進秀麗隱桿線蟲壽命之調控 (Reduced ribose-5-phosphate isomerase A expression in specific neurons and time points promotes longevity in C. elegans) | NTHU NDLTD | 碩逕博 | 4.47 |
核糖-5-磷酸異構酶(RPIA)(Ribose-5-phosphate isomerase A (RPIA))、磷酸戊糖途徑(PPP)(pentose phosphate pathway (PPP))、細胞自噬(autophagy)(autophagy)、單磷酸腺苷活化蛋白質激酶(AMP activated protein kinase, AMPK)(AMP activated protein kinase (AMPK))、雷帕黴素標靶蛋白(Target of rapamycin, TOR)(target of rapamycin (TOR))、興奮性神經元(excitatory neurons)、長壽(lifespan)、線蟲(C. elegans.) 核糖-5-... | ||||
110 | 降低神經中... 降低神經中酪蛋白激酶I α表現量延長果蠅壽命並減緩β澱粉樣蛋白造成的短命 (Knockdown of casein kinase I alpha in neurons promotes longevity and alleviates beta-amyloid-caused shortened lifespan in Drosophila) | NTHU NDLTD | 碩 | NaN |
酪蛋白激酶I α(Casein kinase Iα)、長壽(longevity)、老化(aging)、果蠅(Drosophila) 酪蛋白激酶... | ||||
110 | 過度表現果... 過度表現果蠅粒線體丙酮酸載體1基因對於長壽及壓力反應之研究 (The study of mitochondrial pyruvate carrier 1 overexpression on longevity and stress response in Drosophila) | NTHU NDLTD | 碩 | 0.99 |
粒線體丙酮酸載體1(mitochondrial pyruvate carrier 1)、長壽(longevity)、果蠅(Drosophila)、粒線體(mitochondria)、壓力反應(stress response) 粒線體丙酮... | ||||
110 | 賴氨酸缺乏... 賴氨酸缺乏蛋白激酶 1 訊息在癌轉移和血管新生的探討及開發新穎的抗癌策略 (The investigation of the WNK lysine-deficient protein kinase 1 signaling in metastasis and angiogenesis to develop novel anti-cancer strategies) | NTHU NDLTD | 碩 | 1.98 |
斑馬魚(zebrafish)、賴氨酸缺乏蛋白激酶 1(angiogenesis)、血管新生(WNK1)、癌轉移(metastasis)、肝癌(HCC) 斑馬魚(z... | ||||
110 | 以抗β-類... 以抗β-類澱粉蛋白抗體NP106聯合CB1R反向激動劑CB912治療高脂飲食之阿茲海默症小鼠 (Combination treatment with anti-Aβ antibody NP106 and CB1R inverse agonist CB912 in a high-fat diet mouse model of Alzheimer’s disease) | NTHU NDLTD | 碩 | 1.97 |
阿茲海默症(Alzheimer’s disease)、β-類澱粉蛋白(β-amyloid) 阿茲海默症... | ||||
110 | 探討肝腫瘤... 探討肝腫瘤對蕾莎瓦產生抗藥性之分子調控機制及可能的治療策略 (Explore the Molecular Mechanisms and Therapeutic Strategies of Sorafenib Resistance in Liver Cancer) | NTHU NDLTD | 博 | 7.74 |
蕾莎瓦抗藥性(ANGPTL1)、肝癌(Dicer) 蕾莎瓦抗藥... | ||||
109 | 多種A型核... 多種A型核纖層蛋白突變導致肌失養症的功能和分子分析於斑馬魚模式之研究 (Functional and molecular analysis of LMNA mutations related muscular dystrophy in zebrafish) | NTHU NDLTD | 碩 | 1.98 |
斑馬魚(zebrafish)、高通量基因克隆技術(Gateway Cloning)、A型核纖層蛋白(LMNA)、肌失養症(muscular dystrophy) 斑馬魚(z... | ||||
109 | 口腔癌細胞... 口腔癌細胞衍生的外泌體 miR-421藉由血管內皮細胞 HS2ST1調控血管生成的機制探討 (The Role of Oral Squamous Cell Carcinoma-Derived Exosomal miR-421 in Angiogenesis via Targeting HS2ST1 in Vascular Endothelial Cells) | NTHU NDLTD | 碩 | 1.96 |
OSCC(OSCC)、外泌體(exosome)、miR-421(miR-421)、HS2ST1(HS2ST1)、血管新生(angiogenesis) OSCC(... | ||||
109 | 秀麗隱桿線... 秀麗隱桿線蟲之ptr-23基因所介導之壽命調控及氧化壓力耐受性之研究 (The study of PaTched Related family 23-mediated lifespan regulation and oxidative stress tolerance in C. elegans) | NTHU NDLTD | 碩 | 1.96 |
磷脂酰肌醇運輸蛋白質(ptr-23)、雷帕黴素標靶訊號(PITP)、胰島素生長因子訊號(target of rapamycin signaling)、磷酸化AKT蛋白質(insulin/insulin-like growth factor signaling)、長壽(phosphorylated AKT)、秀麗隱桿線蟲(longevity) 磷脂酰肌醇... | ||||
109 | C型凝集素... C型凝集素連結埃及斑蚊的免疫及生殖過程 (C-Type Lectins Link Immunological and Reproductive Processes in Aedes aegypti) | NTHU NDLTD | 博 | 7.14 |
埃及斑蚊(Aedes aegypti)、C型凝集素(C-type lectin)、蟲媒病毒(arbovirus)、免疫反應(immune response)、生殖細胞(germline)、繁殖(reproduction)、資源權衡(resource trade-off) 埃及斑蚊(... | ||||
108 | 研究在不同... 研究在不同組織及時間表現酪蛋白激酶1a於果蠅壽命之調控 (The study of casein kinase 1 alpha expression via spatial and temporal modulation on lifespan regulation in Drosophila) | NTHU NDLTD | 碩 | 2.00 |
長壽(aging)、果蠅(longevity)、線蟲(Drosophila)、酪蛋白激酶(C. elegans) 長壽(ag... | ||||
108 | 開發 Ma... 開發 Macrophage Colony-Stimulating Factor-1 受體 (CSF-1R) 之單株抗體以抑制 M2 巨噬細胞的 CSF-1R 訊息傳遞 (Development of Anti-Macrophage Colony-Stimulating Factor-1 Receptor (CSF-1R) Monoclonal Antibody to Neutralize CSF-1-Dependent Signaling in M2 Macrophages) | NTHU NDLTD | 碩 | 1.98 |
CSF-1R(CSF-1R)、單株抗體(monoclonal antibody)、腫瘤微環境 (TME)(tumor microenvironment (TME))、腫瘤相關巨噬細胞 (TAM)(tumor associated macrophage (TAM)) CSF-1... | ||||
108 | 以斑馬魚動... 以斑馬魚動物模式研究端粒酶過度表達誘導肝癌發生的功能分析 (Functional analysis of telomerase overexpression in hepatocarcinogenesis using transgenic fish) | NTHU NDLTD | 碩 | 1.96 |
斑馬魚(zebrafish)、肝細胞癌(HCC)、端粒酶(telomerase)、p53 腫瘤抑制蛋白(p53)、細胞增殖(cell proliferation)、高通量基因克隆技術(Gateway Cloning) 斑馬魚(z... | ||||
107 | 探討由微小... 探討由微小核醣核酸所調控之DDR1及CBX8於口腔癌中所扮演的角色 (The miRNA-Mediated DDR1 and CBX8 Pathways and Their Roles in Oral Cancer) | NTHU NDLTD | 博 | 6.99 |
口腔癌(Oral cancer)、DDR1(DDR1)、microRNA(microRNA)、CBX8(CBX8)、MIPOL1(MIPOL1) 口腔癌(O... | ||||
107 | 探討特定神... 探討特定神經迴路抑制視網膜退化B基因表現於果蠅長壽之研究 (Investigation of the specific neural circuits for retinal degeneration B knockdown-mediated longevity in Drosophila) | NTHU NDLTD | 碩 | 1.99 |
老化(Aging)、雷帕黴素標靶訊號傳遞路徑(Target of rapamycin (TOR) signaling pathway)、視網膜退化B基因(retinal degeneration B)、果蠅(Drosophila) 老化(Ag... | ||||
107 | 利用斑馬魚... 利用斑馬魚模式研究脂肪酸轉位酶過度表達對脂質積累和肝癌形成的功能分析 (The functional and molecular analyses of fatty acid translocase overexpression transgenic zebrafish on lipid accumulation and liver cancer development) | NTHU NDLTD | 碩 | 1.96 |
肝癌(Hepatocellular carcinoma)、非酒精性肝炎(non-alcoholic fatty liver disease)、脂肪酸轉位酶(CD36 overexpression)、高脂飲食(High fat diet)、斑馬魚(zebrafish) 肝癌(He... | ||||
107 | 利用斑馬魚... 利用斑馬魚模式研究原肌球蛋白3的新生突變造成先天性肌病 (The investigation of a de novo mutation in human tropomyosin 3 of congenital myopathy in transgenic zebrafish) | NTHU NDLTD | 碩 | 1.96 |
先天性肌病(Congenital myopathy)、原肌球蛋白3(tropomyosin 3)、斑馬魚(zebrafish) 先天性肌病... | ||||
107 | 探討 Fi... 探討 Fis1 對粒線體型態以及蛋白質恆定的影響 (Role of Fis1 in determining mitochondrial morphology and regulating protein homeostasis.) | NTHU NDLTD | 碩 | 1.95 |
粒線體(Mitochondria)、聚集體(Aggresome)、電子傳遞鏈(ETC)、蛋白質恆定(Protein homeostasis) 粒線體(M... | ||||
107 | 系統性研究... 系統性研究肝X受體訊息調控血管新生與CD44調控攝護腺癌中歐洲紫杉醇抗藥性促進之轉移所扮演的角色 (Systematic Analysis of the Roles of Liver X Receptor Signaling in Angiogenesis Regulation and CD44 in Regulation of Docetaxel- Resistance-enhanced Prostate Cancer Metastasis) | NTHU NDLTD | 博 | 3.95 |
血管新生(Angiogenesis)、癌症轉移(Metastasis)、肝X受體(Liver X receptor)、攝護腺癌(Prostate cancer)、歐洲紫杉醇(Docetaxel) 血管新生(... | ||||
106 | EGFR與... EGFR與c-Met雙重激酶抑制劑及DBPR104磷酸前驅物之合成研究 (The Developments of Dual EGFR and c-Met Kinase Inhibitors and DBPR104 Phosphate Prodrugs) | NTHU NDLTD | 碩 | 暫無口試日期 |
激酶抑制劑(EGFR)、藥物化學(c-Met)、有機化學(kinase) 激酶抑制劑... | ||||
106 | 斑馬魚wn... 斑馬魚wnk1對腫瘤誘導血管新生作用的功能分析 (Functional analysis of WNK lysine deficient protein kinase 1 (wnk1) on tumor-induced angiogenesis in zebrafish) | NTHU NDLTD | 碩 | 1.95 |
斑馬魚(Zebrafish)、腫瘤誘導血管新生(Tumor-induced angiogensis)、離氨酸缺陷型蛋白激酶-1(WNK1)(With-no-K (lysine) protein kinase 1 (WNK1))、大腸直腸癌(Hepatocellular carcinoma (HCC))、肝細胞癌(Colorectal cancer (CRC))、異種移植(Xenotransplant) 斑馬魚(Z... | ||||
106 | 纖維母細胞... 纖維母細胞生長因子第一型調節Nesfatin/催產素的飽足感途徑 (FGF1 mediates nesfatin/oxytocin-related satiety pathway) | NTHU NDLTD | 碩 | 1.95 |
纖維母細胞生長因子(FGF)、肥胖調控(Obesity)、食慾調控(Food intake regulation)、Nesfatin(Nesfatin)、催產素(Oxytocin)、腦室投藥(ICV injection) 纖維母細胞... | ||||
106 | 降低磷脂酰... 降低磷脂酰肌醇循環基因表現量對於線蟲壽命調控之研究 (The study of the reduced expression of phosphatidylinositol cycle genes on C. elegans lifespan regulation) | NTHU NDLTD | 碩 | 4.95 |
磷脂酰肌醇循(phosphatidylinositol cycle)、線蟲(C. elegans)、壽命調控(lifespan regulation) 磷脂酰肌醇... | ||||
106 | 酪蛋白激酶... 酪蛋白激酶1α調控果蠅壽命之研究 (The study of casein kinase I alpha-mediated lifespan regulation in Drosophila) | NTHU NDLTD | 碩 | 2.94 |
酪蛋白激酶1α(Casein kinase I alpha)、果蠅(Drosophila)、壽命(Lifespan)、壓力(Stress) 酪蛋白激酶... | ||||
106 | 磷脂酰肌醇... 磷脂酰肌醇合成酶對果蠅壽命調控之研究 (The study of phosphatidylinositol synthase-mediated longevity in Drosophila) | NTHU NDLTD | 碩 | 1.94 |
果蠅(Drosophila)、壽命週期(lifespan)、磷脂酰肌醇合成酶(PI synthase) 果蠅(Dr... | ||||
106 | 降低磷脂酰... 降低磷脂酰肌醇循環基因表現對於果蠅壽命影響之研究 (The study of the reduced expression of phosphatidylinositol cycle genes on Drosophila lifespan) | NTHU NDLTD | 碩 | 1.94 |
果蠅(drosophila)、壽命(lifespan)、磷脂酉先肌醇循環(phosphatidylinositol cycle) 果蠅(dr... | ||||
106 | 利用CRI... 利用CRISPR/Cas9系統來探討剔除KDM4C對前列腺癌細胞之代謝、移動與侵襲之影響 (Investigate the effect of KDM4C knockout on cancer metabolism, migration, and invasion of prostate cancer cells using CRISPR/Cas9 system.) | NTHU NDLTD | 碩 | 1.90 |
攝護腺癌(KDM4C)、KDM4C(Prostate)、CRISPR(cancer)、Cas9(CRISPR)、前列腺癌(Cas9) 攝護腺癌(... | ||||
106 | 秀麗隱桿線... 秀麗隱桿線蟲之磷脂酰肌醇運輸蛋白質-1基因介導壽命調控之機制研究 (The mechanism study of phosphatidylinositol transfer protein-1 mediated lifespan regulation in Caenorhabditis elegans) | NTHU NDLTD | 博 | 5.87 |
磷脂酰肌醇運輸蛋白質-1(Phosphatidylinositol transfer protein-1)、長壽(Longevity)、雷帕黴素標靶(Target of rapamycin)、胰島素/類胰島素生長因子訊號(Insulin/ insulin-like growth factor (IGF-1) signaling)、秀麗隱桿線蟲(C. elegans) 磷脂酰肌醇... | ||||
106 | 核醣-5-... 核醣-5-磷酸異構酶A在大腸直腸癌和肝細胞癌形成中的分子機制 (The molecular mechanisms of ribose-5-phosphate isomerase A in the formation of colorectal cancer and hepatocellular carcinoma) | NTHU NDLTD | 博 | 6.74 |
核醣-5-磷酸異構酶A(Ribose-5-phosphate isomerase A)、大腸直腸癌(colorectal cancer)、肝細胞癌(hepatocellular carcinoma)、β-連環蛋白(β-catenin)、胞外訊號調節激酶(extracellular signal-regulated kinase) 核醣-5-... | ||||
106 | 探討內皮間... 探討內皮間質轉化衍生細胞刺激巨噬細胞產生非典型活化及腫瘤惡性 (Endothelial-Mesenchymal Transition-Derived Cells Promote Macrophage M2-Polarization and Tumor Malignancy) | NTHU NDLTD | 博 | 6.50 |
內皮間質轉化衍生細胞(Endothelial-Mesenchymal Transition-Derived Cells)、巨噬細胞(M2-Polarization)、腫瘤惡性(macrophahge)、腫瘤幹細胞(stemness) 內皮間質轉... | ||||
106 | 利用CRI... 利用CRISPR/Cas9技術孕育DNA-PKcs3A/3A小鼠 (Generation of DNA-PKcs 3A/3A mutant mice by a CRISPR/Cas9 approach) | NTHU NDLTD | 碩 | 2.48 |
人類化老鼠(CRISPR/Cas9)、免疫缺陷鼠(DNA-PKcs)、老鼠胚胎幹細胞(humanized mice) 人類化老鼠... | ||||
105 | 氯硝柳胺抑... 氯硝柳胺抑制大腸直腸癌細胞TCF12–MALAT1誘導的Wnt–beta-Catenin訊號途徑與幹細胞特性 (Niclosamide Suppresses TCF12-MALAT1-Induced Wnt/beta-Catenin Signaling and Colorectal Cancer Cell Stemness) | NTHU NDLTD | 碩 | 2.99 |
TCF12(TCF12)、MALAT1(MALAT1)、氯硝柳胺(niclosamide)、Wnt/β-catenin信號途徑(Wnt/β-catenin signaling pathway)、癌幹細胞特性(cancer cell stemnes) TCF12... | ||||
105 | 探討三株果... 探討三株果蠅抑制多麩醯胺酸鏈毒性之研究 (Characterization of the three suppressors of polyglutamine toxicity in Drosophila) | NTHU NDLTD | 碩 | 1.98 |
多麩醯胺酸鏈(polyglutamine)、亨丁頓舞蹈症(Huntington’s disease)、神經退化性疾病(neurodegenerative disease) 多麩醯胺酸... | ||||
105 | 視網膜退化... 視網膜退化B基因調控果蠅的壽命及老化伴隨的運動能力衰退 (retinal degeneration B regulates lifespan and age-related locomotor decline in Drosophila) | NTHU NDLTD | 碩 | 1.98 |
果蠅(Drosophila)、老化(aging)、長壽(longevity) 果蠅(Dr... | ||||
105 | YAP在肌... YAP在肌肉細胞內調控其增生和分化 (YAP as a molecular regulator of proliferation and differentiation in C2C12 myoblast) | NTHU NDLTD | 碩逕博 | 5.95 |
肌肉前驅細胞(YAP)、分化(C2C12)、增生(myogenesis) 肌肉前驅細... | ||||
105 | 過度表達野... 過度表達野生型和突變型Aurora-A激酶在斑馬魚中誘導肝癌發生進程之研究 (The study of overexpressing wild-type and mutant AURKA induced hepatocarcinogenesis in zebrafish) | NTHU NDLTD | 碩 | 1.95 |
AURKA(AURKA)、斑馬魚(Zebrafish)、肝癌(Hepatocellular carcinoma) AURKA... | ||||
104 | 探討ECM... 探討ECM如何參與粒線體自噬作用與細胞凋亡之關聯性 (ECM modulates the link between mitophagy regulation and apoptosis) | NTHU NDLTD | 碩(外籍生) | 暫無口試日期 |
果蠅(Drosophila)、細胞凋亡(Apoptosis)、細胞自噬(Autophagy) 果蠅(Dr... | ||||
104 | 遺傳篩選抑... 遺傳篩選抑制多麩醯胺酸鏈所誘發粗糙眼之果蠅株 (A genetic screen for the suppressors of polyglutamine-induced rough eyes in Drosophila) | NTHU NDLTD | 碩 | 暫無口試日期 |
多麩醯胺酸鏈(Polyglutamine)、果蠅(Drosophila)、粗糙眼(rough eyes) 多麩醯胺酸... | ||||
104 | 藉由抑制核... 藉由抑制核醣5磷酸異構酵素A減緩癌細胞增殖之蛋白質鑑識 (Identification of proteins involved in the suppressed cell proliferation by knockdown of Ribose-5-phosphate Isomerase A in cancer cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
癌細胞增殖(cancer cell proliferation)、蛋白質鑑識(identification of proteins) 癌細胞增殖... | ||||
104 | 建立核糖-... 建立核糖-5-磷酸異構酶A轉殖基因斑馬魚之肝癌生成研究 (The establishment of ribose-5-phosphate isomerase A transgenic zebrafish for hepatocarcinogenesis study) | NTHU NDLTD | 碩 | 暫無口試日期 |
斑馬魚(zebrafish)、肝癌(hepatocarcinogenesis)、核糖-5-磷酸異構酶A(ribose-5-phosphate isomerase A) 斑馬魚(z... | ||||
104 | 探討ECM... 探討ECM於粒線體自噬作用與神經退化中所扮演的角色 (Role of ECM in mitophagy in muscle and neurodegeneration.) | NTHU NDLTD | 碩 | 暫無口試日期 |
粒線體自噬(mitophagy)、神經退化(neurodegeneration) 粒線體自噬... | ||||
103 | 異檸檬酸去... 異檸檬酸去氫酵素A-1調控線蟲壽命及抗氧化壓力 (Isocitrate Dehydrogenase A-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans) | NTHU NDLTD | 碩 | 暫無口試日期 |
線蟲(Caenorhabditis elegans)、異檸檬酸去氫酵素(Isocitrate Dehydrogenase A-1)、壽命(Lifespan) 線蟲(Ca... | ||||
103 | 蛋⽩ EC... 蛋⽩ ECM 的結構與功能在粒線體膨⼤與聚集化現象所扮演之⾓⾊探討 (The Structure and Function of ECM Protein in Mitochondrial Enlargement and Clustering) | NTHU NDLTD | 碩 | 暫無口試日期 |
鐵硫離子蛋白(ECM)、粒線體(mitochondria) 鐵硫離子蛋... | ||||
103 | CG320... CG32026基因對果蠅壽命調控及壓力耐受性之研究 (The study of CG32026 on Lifespan Regulation and Stress Tolerance in Drosophila) | NTHU NDLTD | 碩 | 暫無口試日期 |
壽命(aging) 壽命(ag... | ||||
103 | tipto... tiptop基因對VDRC之KK品系果蠅的表現型影響 (The role of tiptop in the phenotypic effects of some VDRC RNAi KK lines in Drosophila) | NTHU NDLTD | 碩 | 暫無口試日期 |
凸眼(bulgy eye) 凸眼(bu... | ||||
103 | 磷酸果糖酵... 磷酸果糖酵素L表現量對肝癌細胞影響之研究 (The study of phosphofructokinase L expression in liver cancer cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
磷酸果糖酵素L(phosphofructokinase L) 磷酸果糖酵... | ||||
103 | 利用斑馬魚... 利用斑馬魚肝癌模式平台鑑定出兩種抗血管新生、抗增殖及抗轉移的新穎小分子藥物 (Identification of two novel small compounds with anti-angiogenesis, anti-proliferation and anti-migration for liver cancer model in zebrafish platform) | NTHU NDLTD | 碩 | 暫無口試日期 |
斑馬魚(zebrafish)、肝細胞癌(hepatocellular carcinoma)、藥物篩選(drug screening) 斑馬魚(z... | ||||
103 | 肝臟X受體... 肝臟X受體激活物T0901317抑制人類臍靜脈內皮細胞血管新生之研究 (The Study of Liver X Receptor Agonist T0901317 Suppresses Angiogenesis of HUVEC Cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
血管新生(Angiogenesis) 血管新生(... | ||||
103 | TAZ對於... TAZ對於前列腺癌細胞遷移、侵入和腫瘤生成中的作用 (A Role for TAZ in Migration, Invasion, and Tumorigenesis of Prostate Cancer Cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
前列腺癌(Prostate cancer) 前列腺癌(... | ||||
102 | 斑馬魚抗肝... 斑馬魚抗肝癌藥物篩選平台之建構 (Establishment of Anti-HCC Drug Screening Platform in Zebrafish) | NTHU NDLTD | 碩 | 暫無口試日期 |
斑馬魚、藥物篩選平台 斑馬魚、藥... | ||||
102 | 抑制肺癌細... 抑制肺癌細胞之核醣5磷酸異構酵素A表現量藉由誘導自嗜作用、細胞凋亡、細胞衰老作用導致減緩細胞生長與集落形成之研究 (Suppression of Ribose-5-phosphate Isomerase A Reduces Cell Proliferation and Colony Formation Ability by Induction of Autophagy, Apoptosis and Cellular Senescence in Lung Cancer Cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
肺癌(lung cancer)、自噬作用(autophagy)、細胞凋亡(apoptosis) 肺癌(lu... | ||||
102 | 利用咖啡酸... 利用咖啡酸苯乙酯CAPE作為LNCaP 104-R1復發前列腺癌細胞株的治療藥物 (Using Caffeic Acid Phenethyl Ester as a Therapeutic Agent for Suppression of Castration-Resistent LNCaP 104-R1 Prostate Cancer Cell Line) | NTHU NDLTD | 碩 | 暫無口試日期 |
咖啡酸苯乙酯(caffeic acid phenethyl ester)、前列腺癌(prostate cancer)、細胞週期(cell cycle) 咖啡酸苯乙... | ||||
102 | CG145... CG1458於果蠅老化、粒線體動態變化與細胞死亡扮演之角色探討 (Roles of CG1458 in Drosophila Aging, Mitochondrial Dynamics and Cell Death) | NTHU NDLTD | 碩 | 暫無口試日期 |
鐵硫蛋白、粒線體、細胞凋亡、老化 鐵硫蛋白、... | ||||
101 | 抑制異檸檬... 抑制異檸檬酸去氫酶A-1表現降低線蟲壽命及抗氧化壓力 (Knockdown of Isocitrate Dehydrogenase A-1 Reduces Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans) | NTHU NDLTD | 碩 | 暫無口試日期 |
異檸檬酸去氫酶(TCA cycle)、三羧酸循環(Isocitrate Dehydrogenase)、氧化壓力(IDHA-1) 異檸檬酸去... | ||||
101 | 自噬相關基... 自噬相關基因於減緩果蠅中因降低轉二羥丙酮酵素表現而誘發細胞凋亡之研究 (The role of autophagy-related genes in attenuation of transaldolase-knockdown mediated apoptosis in Drosophila) | NTHU NDLTD | 碩 | 暫無口試日期 |
轉二羥丙酮酵素(Transaldolase)、細胞凋亡(Apoptosis)、細胞自噬(Autophagy)、細胞自噬基因6(Atg6)、細胞自噬基因14(Atg14)、泛素蛋白酶體系統(ubiquitin proteasome system (UPS)) 轉二羥丙酮... | ||||
101 | 篩選果蠅降... 篩選果蠅降低轉醛醇縮酶所造成凸眼之遺傳調控因子 (A screen for the genetic modifiers on the transaldolase knockdown mediated bulgy eye in Drosophila) | NTHU NDLTD | 碩 | 暫無口試日期 |
果蠅(Drosophila)、轉醛醇縮酶(transaldolase) 果蠅(Dr... | ||||
101 | 探討內皮素... 探討內皮素-1和α-甘露糖苷酶IC在肝癌症形成時的分子作用機制 (The study of the molecular mechanisms of endothelin-1 and alpha-1,2 mannosidase IC in liver cancer formation) | NTHU NDLTD | 碩 | 暫無口試日期 |
肝癌(liver cancer)、肝細胞癌(Hepatocellular Carcinoma)、內皮素-1(endothelin 1)、甘露糖苷酶(mannosidase)、內質網壓力(ER stress) 肝癌(li... | ||||
101 | 利用激酶與... 利用激酶與去磷酸酶的shRNA基因庫篩選出能影響細胞侵襲性的基因 (Identification of genes involved in cell invasion by screening an shRNA library of kinases and phosphatases) | NTHU NDLTD | 碩 | 暫無口試日期 |
胰腺癌(shRNA)、慢病毒(RNAi)、激酶(lentivirus)、去磷酸酶(kinases)、RNA干擾(phosphatases)、侵襲(invasion) 胰腺癌(s... |