政府計畫（GRB），建議「依年度遞減排序」，以查看最新的研究方向。
| 畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
|---|---|---|---|---|
| 關鍵字 | ||||
| 111 | 短胜肽對酯... 短胜肽對酯類及磷酯類水解反應的催化效率探討 (Design of Short Peptides as Catalysts for Ester and Phosphoester Hydrolysis) | NTHU NDLTD | 碩 | 1.99 |
胜肽(peptide)、水凝膠(hydrogel)、催化(catalysis)、酯類(ester)、磷酯類(phosphoester) 胜肽(pe... | ||||
| 111 | 利用交聯作... 利用交聯作用和組胺酸-金屬配位提升膠原蛋白模擬胜肽自組裝之探討 (Study of Covalent Cross-Link and Histidine-Metal Coordination on Self-assembly of Collagen-Mimetic Peptides) | NTHU NDLTD | 碩 | 1.99 |
膠原蛋白(Collagen Mimetic Peptide)、金屬配位(Metal-coordination)、交聯作用(Cross-linking)、自組裝(Self-assembly)、藥物運輸(Drug delivery) 膠原蛋白(... | ||||
| 111 | 聚脯胺酸結... 聚脯胺酸結合棕櫚酸之自組裝脂肽作為人工水解酶的催化活性的探討 (Study of Self-Assembled Lipopeptides Containing Polyproline and Palmitic Acid as an Artificial Hydrolase) | NTHU NDLTD | 碩 | 1.99 |
脂肽(Lipopeptides)、人工水解酶(Artificial Hydrolase)、聚脯胺酸(Polyproline)、自組裝(Self-Assembled) 脂肽(Li... | ||||
| 111 | 探討Cat... 探討Cation-π作用力位向對膠原蛋白三股螺旋之影響 (Evaluation of Direction Dependent Cation-π Interactions within Collagen Triple Helices) | NTHU NDLTD | 碩 | 1.99 |
膠原蛋白(collagen)、三股螺旋(triple helix)、陽離子-π 作用力(cation-π interaction)、異源三股螺旋(heterotrimer) 膠原蛋白(... | ||||
| 110 | 含聚脯胺酸... 含聚脯胺酸之自組裝胜肽對酯類及磷酯類水解反應的催化效率探討 (Design of Polyproline-Containing Self-Assembling Peptides as Catalysts for Ester and Phosphoester Hydrolysis) | NTHU NDLTD | 碩 | 1.98 |
胜肽(Peptide)、聚脯胺酸胜肽(Polyproline)、自組裝胜肽(Self-assembly)、人工水解酶(Artificial hydrolases)、催化(Catalysis) 胜肽(Pe... | ||||
| 110 | 硫脯胺酸及... 硫脯胺酸及其氧化衍生物對膠原蛋白三股螺旋結構及穩定度影響之探討 (Consequences of Incorporating Thiaproline and Its Oxidative Derivatives into Collagen Triple Helices) | NTHU NDLTD | 碩 | 1.97 |
硫脯胺酸(Thiaproline)、膠原蛋白模擬胜肽(Collagen) 硫脯胺酸(... | ||||
| 110 | 利用組胺酸... 利用組胺酸-金屬配位和非共價鍵作用力調控膠原蛋白模擬胜肽自組裝及藥物包覆之探討 (Modulating the Self-Assembly of Collagen-Mimetic Peptides via Histidine-Metal Coordination and Noncolvalent Interactions, and Study of Their Drug Encapsulation) | NTHU NDLTD | 碩 | 1.97 |
聚脯胺酸(Polyproline II)、胜肽(Peptide)、自組裝(Self-assembly)、組胺酸-金屬配位(Histidine-metal coordination)、膠原蛋白模擬胜肽(Collagen mimetic peptides)、藥物包覆(Drug encapsulation) 聚脯胺酸(... | ||||
| 110 | T細胞酪胺... T細胞酪胺酸去磷酸酶的異位調控：無結構區域造成之自我活性抑制及整聯蛋白alpha-1碳端所促進之酵素活化 (The intrinsic disordered C-terminal tail regulates the catalytic activity of T-cell protein tyrosine phosphatase: from allosteric auto-inhibition to activation by Integrin alpha-1) | NTHU NDLTD | 碩逕博 | 7.42 |
晶體結構(T-Cell Protein Tyrosine Phosphatase)、蛋白酪氨酸磷酸酶(Crystal structure)、磷酸酶活性(Protein tyrosine phosphatase)、催化活性(TCPTP)、變構調節(PTPN2)、自動調節/自動抑制(Phosphatase activity)、核磁共振波譜(Catalytic activity) 晶體結構(... | ||||
| 109 | 甘胺酸變異... 甘胺酸變異對膠原蛋白異源三股螺旋影響之探討 (Effects of mutating glycine residues on collagen heterotrimers) | NTHU NDLTD | 碩 | 2.21 |
甘胺酸變異(mutation of glycine)、膠原蛋白(collagen)、同源三股螺旋(homotrimer)、異源三股螺旋(heterotrimer)、Cation-π作用力(cation-π interactions) 甘胺酸變異... | ||||
| 109 | 利用雙股胜... 利用雙股胜肽與非共價作用力誘導膠原蛋白異源三股螺旋摺疊之探討 (Study of using dimeric peptides and non-covalent interactions to induce the folding of collagen heterotrimers) | NTHU NDLTD | 碩 | 1.98 |
膠原蛋白(collagen)、胜肽(peptide)、雙股胜肽(heterotrimer)、異源三股螺旋(cation-pi)、三股螺旋(refold) 膠原蛋白(... | ||||
| 109 | 利用陽離子... 利用陽離子-π作用力和雙硫鍵誘導膠原蛋白異源三股螺旋摺疊之探討 (Using cation-π interactions and disulfide bonds to induce the folding of collagen heterotrimers) | NTHU NDLTD | 碩 | 1.98 |
膠原蛋白(collagen)、異源三股螺旋(heterotrimers)、陽離子-π(cation-π)、雙硫鍵(disulfide) 膠原蛋白(... | ||||
| 109 | 聚脯胺酸胜... 聚脯胺酸胜肽結合β褶板之自組裝胜肽作為人工水解酶的催化效率探討 (Design of Polyproline Peptide/ β-sheet Conjugated Assemblies as Artificial Hydrolases) | NTHU NDLTD | 碩 | 1.98 |
胜肽(Peptide)、聚脯胺酸胜肽(Polyproline peptide)、β褶板(β-sheet)、人工水解酶(Artificial hydrolases)、催化(Catalysis)、自組裝(Self-assembly) 胜肽(Pe... | ||||
| 109 | 金屬誘導短... 金屬誘導短序列膠原蛋白模擬胜肽自組裝與其對酯類水解反應之催化活性探討 (Metal-Induced Self-Assembly of Short Collagen-Mimetic Peptides and Their Hydrolytic Catalysis Evaluation) | NTHU NDLTD | 碩 | 3.09 |
膠原蛋白模擬胜肽(collagen mimetic peptides)、自組裝(self-assembly)、組胺酸-金屬配位鍵(histidine-metal coordination)、酯類水解(ester hydrolysis) 膠原蛋白模... | ||||
| 108 | 含吡啶官能... 含吡啶官能基的膠原蛋白模擬胜肽設計與其結構自組裝及對酯類水解催化之探討 (Design of Pyridine Moiety Containing Collagen-Mimetic Peptides for Self-Assembly and the Catalysis on Ester Hydrolysis Study) | NTHU NDLTD | 碩 | 1.98 |
膠原蛋白(collagen)、吡啶(pyridine)、胜肽(peptide)、自組裝(self-assembly)、酯類水解催化(ester hydrolysis) 膠原蛋白(... | ||||
| 108 | 結合聚脯胺... 結合聚脯胺酸胜肽與自組裝胜肽之水解酶設計和其催化效率探討 (Design of Polyproline Based Peptides and Self-Assembling Structures as Catalysts for Ester Hydrolysis) | NTHU NDLTD | 碩 | 1.98 |
胜肽(peptide)、聚脯胺酸(polyproline)、自組裝(self-assembling)、催化(catalysis)、酯類水解(ester)、立體電子效應(stereoelectronic) 胜肽(pe... | ||||
| 108 | 利用Cat... 利用Cation-π作用力穩定膠原蛋白及誘導其異源三股螺旋摺疊之探討 (Study of cation-π interactions to stabilize collagen and induce the folding of heterotrimers) | NTHU NDLTD | 碩 | 1.98 |
膠原蛋白(collagen)、三股螺旋(peptide)、胜肽(heterotrimer)、穩定作用力(homotrimer)、作用力位向及指向(stabilization)、異源三股螺旋(cation-pi) 膠原蛋白(... | ||||
| 108 | 一、 開發... 一、 開發具腫瘤標靶能力之硼中子捕獲治療藥劑 二、 Leucettamine B類似物的合成與抗癌活性評估 (I. Development of tumor-targeting agents for Boron Neutron Capture Therapy II. Synthesis and bioevaluation of Leucettamine B analogs as the potential anti-cancer agents) | NTHU NDLTD | 博 | 6.56 |
抗癌藥物(anti-cancer drugs)、硼簇(boron cluster)、碳硼烷(carborane)、硼中子捕獲治療(Boron Neutron Capture Therapy) 抗癌藥物(... | ||||
| 107 | 膠原蛋白模... 膠原蛋白模擬胜肽與其自組裝結構對酯類水解反應的催化效率探討 (Study of Collagen-Mimetic Peptides and Their Supramolecular Structures on Catalyzing Ester Hydrolysis) | NTHU NDLTD | 碩 | 1.96 |
膠原蛋白模擬胜肽(collagen-mimetic peptide)、人工水解酶(artifical hydrloase)、自組裝結構(self-assembly structure) 膠原蛋白模... | ||||
| 107 | 利用cat... 利用cation-π作用力及交聯作用提升膠原蛋白膜擬胜肽自組裝與不同位向cation-π作用力對三股螺旋穩定度之探討 (Study of cation-π interactions and cross linking on the self-assembly of collagen-mimetic peptides and the orientation dependent of cation-π interactions on the stability of collagen triple helix) | NTHU NDLTD | 碩 | 2.96 |
膠原蛋白(collagen)、陽離子-π 作用力(cation-π interaction)、水凝膠(hydrogel)、三股螺旋(triple helix) 膠原蛋白(... | ||||
| 107 | 末端帶電荷... 末端帶電荷胺基酸於膠原蛋白三股螺旋穩定度之探討 (Effects of Terminal Charged Residues on the Stability of Collagen Triple Helices) | NTHU NDLTD | 碩 | 1.96 |
膠原蛋白(Collagen)、三股螺旋(Triple helices)、靜電交互作用(Electrostatic interaction) 膠原蛋白(... | ||||
| 107 | 聚脯胺酸胜... 聚脯胺酸胜肽的探討：末端帶電荷胺基酸對結構之影響、與人類Pin1 WW區間的結合親和力及作為酯類水解酶之設計 (Study of polyproline peptides: the effects of terminal charged residues on conformation, the binding affinity for human Pin1 WW domain and the design of artificial esterases) | NTHU NDLTD | 碩逕博 | 6.60 |
脯胺酸(Proline)、聚脯胺酸構形(Polyproline conformation)、結合親和力(Binding affinity)、人工酯類水解酶(Artificial esterase) 脯胺酸(P... | ||||
| 107 | Catio... Cation−π作用力誘導膠原蛋白異源三股螺旋之摺疊探討 (Study of Cation−π Interaction Induced Folding of the Collagen Heterotrimers) | NTHU NDLTD | 碩逕博 | 6.47 |
膠原蛋白模擬胜肽(collagen mimetic peptides)、異源三股螺旋(heterotrimer)、陽離子−π作用力(cation−π interactions)、圓二色光譜儀(circular dichroism)、摺疊熱力學(folding thermodynamics) 膠原蛋白模... | ||||
| 106 | 巨分子擁擠... 巨分子擁擠效應對不同胜肽結構影響之探討 (Macromolecular Crowding Effect on Different Peptide Structures) | NTHU NDLTD | 碩 | 1.99 |
擁擠效應(crowding effect)、形狀(shape)、圓二色光譜(HP36)、熱變性(WW-domain)、化學變性(collagen)、蛋白質構形(Ficoll) 擁擠效應(... | ||||
| 106 | 利用含組胺... 利用含組胺酸之膠原蛋白模擬胜肽進行異源三股螺旋摺疊和酯類水解催化反應的探討 (Study of Heterotrimeric Folding and Ester Hydrolysis Catalysis using Histidine-Containing Collagen-Mimetic Peptides) | NTHU NDLTD | 碩 | 2.97 |
膠原蛋白(collagen)、酯類水解催化(ester hydrolysis catalysis)、異源三股螺旋(heterotrimer)、組胺酸(histidine) 膠原蛋白(... | ||||
| 105 | Catio... Cation-π作用力及甘胺酸變異對AAB型膠原蛋白異源三股螺旋穩定性之探討 (Effects of cation-π interactions and mutation of glycine residues on the stability of AAB-type collagen heterotrimers) | NTHU NDLTD | 碩 | 1.97 |
Cation-π作用力(Cation-π interactions)、甘胺酸變異(mutation of glycine)、膠原蛋白(collagen)、AAB型異源三股螺旋(AAB-type heterotrimers) Catio... | ||||
| 105 | 膠原蛋白模... 膠原蛋白模擬胜肽與硼烷共軛化合物的製備及雙硫鍵與cation-π作用力對膠原蛋白異源三股螺旋摺疊探討 (Preparation of the collagen-mimetic peptide-borane conjugate and the effects of disulfides and cation-π interactions on the folding of collagen heterotrimers) | NTHU NDLTD | 碩 | 1.97 |
硼烷共軛化合物(borane conjugate)、雙硫鍵(disulfides)、異源三股螺旋(heterotrimers) 硼烷共軛化... | ||||
| 105 | 含組胺酸之... 含組胺酸之聚脯胺酸短胜肽與類膠原蛋白胜肽對酯類水解反應的催化效率探討 (Design of Histidine-Containing Polyproline and Collagen-Mimetic Peptides as Enzymes for Catalyzing Ester Hydrolysis) | NTHU NDLTD | 碩 | 1.95 |
聚脯胺酸(Polyproline)、膠原蛋白(Collagen)、酯類水解(Ester hydrolysis)、人工水解酶(Artificial enzyme)、催化(Catalysis) 聚脯胺酸(... | ||||
| 104 | 利用交聯方... 利用交聯方法探討雞絨毛蛋白片段HP36的結構 (Studying the Unfolded Structure of Villin Headpiece Fragment HP36 by a Cross-linking Approach) | NTHU NDLTD | 碩 | 無口試日期 |
雞絨毛蛋白(villin)、胜肽(HP36)、交聯(peptide)、摺疊機制(cross-linking)、穩定度(folding mechanism) 雞絨毛蛋白... | ||||
| 104 | 低配位多金... 低配位多金屬錯合物的合成 (Synthesis of Low - Coordinate Multi-nuclear Complexes) | NTHU NDLTD | 碩 | 無口試日期 |
多金屬錯合物(Multi-nuclear Complexes) 多金屬錯合... | ||||
| 104 | 金屬誘導膠... 金屬誘導膠原蛋白模擬胜肽自組裝與其結構對酯類水解反應之催化活性探討 (Metal-Induced Self-Assembly of Collagen-Mimetic Peptides and Their Catalytic Activity for Ester Hydrolysis) | NTHU NDLTD | 碩 | 無口試日期 |
膠原蛋白(collagen)、自組裝(self-assembly)、金屬(metal)、酯類水解(ester hydrolysis) 膠原蛋白(... | ||||
| 103 | 羥脯胺酸醣... 羥脯胺酸醣化修飾對膠原蛋白穩定性與自組裝之影響 (The effects of glycosylated (2S,4R)-hydroxyproline on collagen stability and self-assembly) | NTHU NDLTD | 碩 | 無口試日期 |
膠原蛋白(collagen)、半乳糖(galactose) 膠原蛋白(... | ||||
| 103 | 探討高胺酸... 探討高胺酸置換對於胜肽結構的影響及研究 Prion 蛋白片段作為醯基轉化催化劑之效益 (The effect of (S)-piperidine-2-carboxylic acid on peptide structure and the catalytic activity of Prion protein fragments on acyl transfer reaction) | NTHU NDLTD | 碩 | 無口試日期 |
胜肽、高胺酸、脯胺酸 胜肽、高胺... | ||||
| 103 | 探討高自組... 探討高自組裝性之短胜肽序列對膠原蛋白模擬胜肽摺疊和自組裝性質影響 (The Effects of High Self-Assembled Oligopeptides on the Folding and Self-Assembly of Collagen Mimetic Peptides) | NTHU NDLTD | 碩 | 無口試日期 |
膠原蛋白(Collagen)、細胞毒性實驗(Cytotoxicity experiment)、自組裝(Self-assemble)、三股螺旋(Triple helix) 膠原蛋白(... | ||||
| 102 | 膠原蛋白模... 膠原蛋白模擬胜肽對貝它類澱粉蛋白 Aβ(16-22) 聚集影響的探討 (The effects of collagen mimetic peptides on the aggregation of Aβ(16-22)) | NTHU NDLTD | 碩 | 無口試日期 |
膠原蛋白模擬胜肽對貝它類澱粉蛋白 Aβ(16-22) 聚集影響的探討(The effects of collagen mimetic peptides on the aggregation of Aβ(16-22)) 膠原蛋白模... | ||||
| 102 | 溶液酸鹼值... 溶液酸鹼值對人類 Pin1 穩定性及含脯胺酸衍生物之基質對其酵素活性效率影響 (Study of Human Pin1: pH-dependent Stability and the Impacts of 4-Substituted Proline Derivatives on the Catalytic Efficiency) | NTHU NDLTD | 碩 | 無口試日期 |
順反異構酶(pin1)、脯胺酸(catalytic efficiency)、催化效率(proline)、胜肽(undefined) 順反異構酶... | ||||
| 101 | 液液微萃取... 液液微萃取法搭配極致效能液相層析儀分析水樣中的硝基酚類化合物 (Determination of nitrophenols in water sample using dispersive liquid-liquid microextraction combined with UPLC) | NTHU NDLTD | 碩 | 無口試日期 |
分散液液微萃取(dispersive liquid-liquid microextraction)、硝基酚類化合物(nitrophenols)、低濃度界面活性劑輔助乳化(water with low concentration surfactant as disperse solvent)、垂直震盪器輔助乳化(up-and-down shaker assisted microextraction) 分散液液微... | ||||
| 101 | 利用實驗與... 利用實驗與計算探討脯胺酸衍生物對聚脯胺酸以及β-hairpin 結構之影響 (Using experimental and computational approaches to study the effects of proline derivatives on the structure of polyproline and β-hairpin) | NTHU NDLTD | 碩 | 無口試日期 |
脯胺酸(proline)、聚脯胺酸(polyproline)、n→π* 作用力(n→π* interactions)、立體電子效應(stereoelectronic effects)、DFT(DFT) 脯胺酸(p... | ||||
| 101 | 利用組胺酸... 利用組胺酸-金屬配位作用來進行膠原蛋白自組裝之探討 (Self-Assembly of Collagen-Related Peptides by Metal-Histidine Coordination) | NTHU NDLTD | 碩 | 無口試日期 |
膠原蛋白(collagen)、組胺酸(histidine)、金屬配位(coordination)、纖維(fiber)、自組裝(self-assembly) 膠原蛋白(... |