政府計畫（GRB），建議「依年度遞減排序」，以查看最新的研究方向。
| 畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
|---|---|---|---|---|
| 關鍵字 | ||||
| 112 | 抗菌肽W5... 抗菌肽W5K11白介素2融合蛋白以及白介素2之表現和其活性之探討 (Expression and Characteristic of W5K11-Interleukin-2(IL-2) fusion protein and IL-2) | NTHU NDLTD | 碩 | 2.84 |
免疫療法(Cancer immunotherapy)、白介素2(anticancer peptide)、抗菌胜肽(interleukin-2 (IL-2))、癌症治療(cancer treatment)、抗癌胜肽(undefined) 免疫療法(... | ||||
| 112 | CXC受體... CXC受體拮抗劑(RP4)在胰臟癌治療中的作用：抑制抗藥性和調節癌症幹细胞的特性 (CXC receptor antagonist (RP4) in pancreatic cancer therapy: Inhibition of drug resistance and regulation of cancer stem cell properties) | NTHU NDLTD | 碩 | 1.84 |
胰臟癌(Pancreatic cancer)、白细胞介素-8(Interleukin-8(IL-8))、CXC受體1/2(CXCR1/2)、拮抗劑(Antagonist)、抗藥性(Chemoresistance)、癌症幹細胞(Cancer stem cells(CSCs)) 胰臟癌(P... | ||||
| 112 | 溶瘤肽在小... 溶瘤肽在小鼠黑色素瘤模型中誘導免疫原性細胞死亡以及遠端效應 (Oncolytic Peptides Induced Immunogenic Cell Death and Abscopal Effect in a Murine Melanoma Model) | NTHU NDLTD | 碩 | 0.84 |
黑色素瘤(Melanoma)、抗菌肽(Antimicrobial Peptides)、融瘤肽(Oncolytic Peptides)、免疫原性細胞死亡(Immunogenic Cell Death)、免疫檢查點抑制劑(Immune Checkpoint Inhibitors)、遠端效應(Abscopal Effect) 黑色素瘤(... | ||||
| 112 | 探討那西肽... 探討那西肽搭配順鉑或溶瘤肽對黑色素瘤的免疫原性細胞死亡及於小鼠黑色素瘤模型的抗腫瘤效果 (Exploring Immunogenic Cell Death and Antitumor Effects of Nosiheptide in Combination with Cisplatin or Oncolytic Peptide in Melanoma, Using a Murine Melanoma Model) | NTHU NDLTD | 碩(提早入學) | 1.89 |
那西肽(nosiheptide)、順鉑(cisplatin)、溶瘤肽(oncolytic peptide)、免疫原性細胞死亡(immunogenic cell death)、黑色素瘤(melanoma)、抗癌活性(anticancer activity) 那西肽(n... | ||||
| 111 | 設計及特性... 設計及特性探討具有抗菌與抗癌潛力的短鏈抗菌胜肽 (Design and Characterization of Short Antimicrobial Peptides with Antimicrobial and Anticancer potential) | NTHU NDLTD | 學逕博 | 4.88 |
抗菌胜肽(antimicrobial peptides)、抗菌胜肽設計(antimicrobial peptide design)、正電胺基酸(positively charged amino acids)、疏水性基團(hydrophobic groups)、抗鹽(anti-salt)、抗癌(anti-cancer)、LPS中和(LPS neutralization) 抗菌胜肽(... | ||||
| 111 | 噻唑抗菌胜... 噻唑抗菌胜肽脂質體聯合順鉑抑制順鉑抗藥性非小細胞肺癌效果及機制探討 (Investigation of the Effect and Mechanisms of Thiazole Antimicrobial Peptide Liposomes in Combination with Cisplatin for Inhibiting Cisplatin Resistance in Non-Small Cell Lung Cancer) | NTHU NDLTD | 碩 | 1.87 |
叉頭盒轉錄因子(FOXM1)、順鉑(cisplatin)、耐藥性(drug resistance)、非小细胞肺癌(non-small cell lung cancer)、A549(A549)、那西肽(nosiheptide)、脂質體(liposome) 叉頭盒轉錄... | ||||
| 111 | CXC-受... CXC-受體拮抗劑(RP4)降低胰臟癌抗藥性與減少癌症幹細胞的特性 (CXC-receptor antagonist (RP4) can diminish chemoresistance and cancer stem cell characteristics in pancreatic cancer) | NTHU NDLTD | 碩 | 1.87 |
胰腺癌(Pancreatic cancer)、白血球介素-8(Interleukin-8)、拮抗劑(Antagonist)、抗藥性(Chemoresistance)、癌症幹細胞(Cancer stem cells)、聯合療法(Combination therapy) 胰腺癌(P... | ||||
| 110 | 抗菌肽在小... 抗菌肽在小鼠纖維肉瘤模型中誘導其免疫原性細胞死亡 (Antimicrobial Peptides Induced Immunogenic Cell Death in A Murine Fibrosarcoma Model) | NTHU NDLTD | 碩 | 1.85 |
抗菌肽(antimicrobial peptides)、抗癌肽(anticancer peptides)、細胞膜完整性(cell membrane integrity)、免疫原性細胞死亡(immunogenic cell death)、抗癌活性(anticancer activity) 抗菌肽(a... | ||||
| 110 | 利用聚乙二... 利用聚乙二醇化脂質體作為噻唑抗菌胜肽之藥物載體應用及特性探討 (Application and Characterization of PEGylated Liposomes as Drug Delivery System for Thiazolyl Antimicrobial Peptides) | NTHU NDLTD | 碩 | 1.85 |
噻唑基肽(thiazolyl peptide)、硫鏈絲菌素(thiostrepton)、那西肽(noisheptide)、抗菌胜肽(antimicrobial peptides)、抗藥性(drug resistance)、脂質體(liposome)、藥物載體(PEGylated)、藥物傳遞(nanodrug carrier)、聚乙二醇化(drug delivery system) 噻唑基肽(... | ||||
| 110 | 天蠶素類抗... 天蠶素類抗菌胜肽之純化與表現方法及其生物活性探討 (High Level Expression and Purification of Cecropin-like Antimicrobial Peptide and Investigation of Its Bioactivity) | NTHU NDLTD | 碩 | 1.85 |
抗菌胜肽(antimicrobial peptides)、天蠶素(cecropin-like peptide)、內含子表現系統(intein expression system)、抗菌活性(antimicrobial activity)、抗內毒素活性(LPS-neutralizing ability) 抗菌胜肽(... | ||||
| 110 | 新型CXC... 新型CXC-受體拮抗劑(RP4)與順鉑聯合療法於癌症治療之影響 (The effect of novel CXC-receptor antagonist (RP4) and combination with cisplatin on hepatocellular carcinoma) | NTHU NDLTD | 碩 | 1.85 |
肝癌(Hepatocellular carcinoma)、白血球介素-8(Interleukin-8)、拮抗劑(antagonist)、順鉑(cisplatin)、聯合療法(combination therapy) 肝癌(He... | ||||
| 109 | 建立PD-... 建立PD-1/PD-L1免疫檢查點抑制劑之篩選平台 (Establish a Screening Platform for PD-1/PD-L1 Immune Checkpoint Inhibitors) | NTHU NDLTD | 碩 | 1.82 |
免疫療法(immunotherapy)、細胞程式性死亡受體 1(programmed cell death protein 1)、細胞程式性死亡-配體 1(programmed cell death ligand 1)、免疫檢查點抑制劑(immune checkpoint inhibitor)、抗藥物抗體(anti-drug antibody)、毒殺型T細胞(cytotoxic T cell) 免疫療法(... | ||||
| 109 | CXCR1... CXCR1/2拮抗劑(RP4)抑制胰臟癌之機制探討 (The mechanism of CXCR1/2 antagonist (RP4) inhibiting the growth in pancreatic cancer) | NTHU NDLTD | 碩 | 1.82 |
介白素-8(Interleukin-8 (IL-8))、CXC受體1/2拮抗劑(CXCR1/2 antagonist)、抗藥性(Chemoresistance)、胰臟癌(Pancreatic cancer)、細胞凋亡(Apoptosis)、訊號傳遞路徑(Cell signaling pathway) 介白素-8... | ||||
| 109 | 探討天蠶素... 探討天蠶素類抗菌胜肽的抗癌活性和細胞免疫原性死亡之影響 (Investigation of the Anti-cancer Activities of Cecropin-like Antimicrobial Peptides and the Effect of Immunogenic Cell Death) | NTHU NDLTD | 碩(外籍生) | 2.50 |
抗癌胜肽(Anticancer peptides)、抗菌胜肽(Antimicrobial peptides)、免疫原性細胞死亡(Immunogenic cell death)、損傷相關分子模式(Damage-associated molecular patterns) 抗癌胜肽(... | ||||
| 109 | 抗菌胜肽抗... 抗菌胜肽抗腫瘤活性和誘導免疫原性細胞死亡的研究 (Studies of Antimicrobial Peptides on the Anti-tumour Activity and Induced Immunogenic Cell Death) | NTHU NDLTD | 碩(提早入學) | 1.99 |
抗菌肽(antimicrobial peptide)、抗腫瘤活性(anti-tumour activity)、先天性免疫系統危險信號(damage-associated molecular patterns)、抗癌肽(bulky non-natural amino acid)、先天免疫原性死亡(immunogenic cell death)、非自然巨大氨基酸(anticancer peptide) 抗菌肽(a... | ||||
| 108 | 抗菌胜肽與... 抗菌胜肽與抗生素合併使用對於多重抗藥性菌株之協同功效及作用機制探討 (Synergistic effects of Antimicrobial Peptides in Combination with Antibiotics against Multidrug-Resistant Strains) | NTHU NDLTD | 碩逕博 | 5.95 |
抗菌胜肽(antimicrobial peptide)、抗藥性(antibiotic resistance)、萬古黴素(vancomycin)、協同作用(synergism)、抗生素(bulky non-nature amino acid)、非自然巨大胺基酸(protein expression)、蛋白質表現(undefined) 抗菌胜肽(... | ||||
| 108 | 重構CXC... 重構CXCR1蛋白脂質體並分析其配體白細胞介素8以及類似物RP4之間的關係 (Reconstituted CXCR1 proteoliposome and analyze the interaction with IL-8 and its analogue RP4) | NTHU NDLTD | 碩 | 1.95 |
介白素8(Interleukin 8)、IL-8類似物(IL-8 analogue)、重構膜蛋白(Reconstituted membrane protein)、蛋白脂質體(Proteoliposomes)、受體CXCR1(CXCR1 receptor)、ELISA親和力實驗(ELISA binding assay) 介白素8(... | ||||
| 108 | 探討CXC... 探討CXC-受體拮抗劑(RP4)在非小細胞肺癌的療效及克服抗藥性作用 (Investigation of the therapeutic effect of CXC-receptor antagonist (RP4) in non-small cell lung cancer and to overcome the drug resistance) | NTHU NDLTD | 碩 | 1.95 |
介白素-8(Interleukin-8)、CXC受體1/2(CXCR 1/2)、拮抗劑(Receptor antagonist)、抗藥性(Drug resistance)、非小細胞肺癌(NSCLC)、癌幹細胞(Cancer stem cell) 介白素-8... | ||||
| 107 | 新穎的CX... 新穎的CXCL8類似物於癌症治療之應用 (A Novel CXCL8 Analogue in Cancer Therapy) | NTHU NDLTD | 碩逕博 | 4.99 |
細胞介白素8類似物(IL-8 analogue)、非小型細胞肺癌(NSCLC)、胰腺癌(pancreatic cancer)、藥物抗性(drug resistance)、艾瑞莎(gefitinib)、健擇(gemcitabine) 細胞介白素... | ||||
| 107 | 新型IL-... 新型IL-8類似物在巨噬細胞共培養系統中抑制胰臟癌之效果 (A novel IL-8 analogue inhibits pancreatic cancer progression in a co-culture system with macrophages) | NTHU NDLTD | 碩 | 1.99 |
白血球介素-8(interleukin-8)、IL-8類似物(IL-8 analog)、腫瘤微環境(tumor microenvironment)、M1/M2巨噬細胞(M1/M2 macrophage)、胰臟管線癌(pancreatic ductal carcinoma)、共培養系統(co-culture system) 白血球介素... | ||||
| 107 | 介白素8及... 介白素8及其類似物與G蛋白偶聯受體CXCR1/CXCR2結合活性試驗的開發 (Binding activity assay development of IL-8 and its analogue with G-protein coupled receptor CXCR1/CXCR2) | NTHU NDLTD | 碩 | 1.99 |
介白素8(interleukin 8)、ELR-CXC趨化素(ELR-CXC chemokine)、IL-8類似物(IL-8 analogue)、發炎(inflammatory)、抗發炎藥物(anti-inflammatory drug)、受體CXCR1(CXCR1 receptor)、受體CXCR2(CXCR2 receptor)、ELISA親和力實驗(ELISA binding assay) 介白素8(... | ||||
| 107 | 探討臨床具... 探討臨床具活性的抗菌胜肽P-113以及其衍生物的作用方式 (Mode of Action of the Clinically Active Antimicrobial Peptide P-113 and its Derivatives) | NTHU NDLTD | 碩逕博 | 6.87 |
抗菌胜肽(Antimicrobial peptide)、核磁共振(Nuclear magnetic resonance) 抗菌胜肽(... | ||||
| 107 | P-113... P-113及其衍生物對多重抗藥性菌株之協同功效 (Synergistic effects of P-113 and its derivatives against multi-drug resistant bacteria) | NTHU NDLTD | 碩 | 1.87 |
萬古黴素(Vancomycin)、抗菌胜肽(antimicrobial peptide)、協同功效(synergistic effect)、多重抗藥性菌株(multi-drug resistant bacteria) 萬古黴素(... | ||||
| 106 | 介白素8與... 介白素8與CXC-受體拮抗劑RP4結構和生物活性之比較 (Comparison of the structure and biological activity of interleukin-8 and CXC-receptor antagonists, RP4) | NTHU NDLTD | 碩 | 1.95 |
介白素8(IL-8)、CXCR1/2(CXCR1/2)、抗發炎藥物(anti-inflammatory drug)、30s loop(30s loop)、ELR motif(ELR motif)、N loop(N loop)、X-光結晶學(X-ray crystallography)、ELISA親合力試驗(ELISA binding assay) 介白素8(... | ||||
| 106 | 新型CXC... 新型CXC受體拮抗劑(RP4)在胰腺癌之效果 (The Effect of Novel CXCR1/2 Antagonist (RP4) in Pancreatic Cancer) | NTHU NDLTD | 碩 | 1.95 |
介白素-8(Interleukin-8 (IL-8))、CXC受體1/2(CXCR1/2)、拮抗劑(antagonist)、抗藥性(chemoresistance)、胰臟管腺癌(Pancreatic ductal adenocarcinoma (PDAC))、癌幹細胞(Cancer stem cell (CSC)) 介白素-8... | ||||
| 106 | 不同電荷分... 不同電荷分布之抗菌胜肽與抗生素對多重耐藥臨床菌株的協同作用 (Synergistic Effect of Antimicrobial Peptides with Different Charge Distribution and Antibiotics Against Multidrug Resistant Clinical Strains) | NTHU NDLTD | 碩 | 1.95 |
抗菌胜肽(antimicrobial peptide)、萬古黴素(vancomycin)、多重抗藥性(multi-drug resistant)、協同功效(combination effect) 抗菌胜肽(... | ||||
| 105 | 短序列抗菌... 短序列抗菌胜肽對具多黏菌素B抗藥性之 革蘭氏陰性菌的殺菌能力及特性探討 (Characterization of short antimicrobial peptides against polymyxin B resistant Gram-negative bacteria) | NTHU NDLTD | 碩 | 1.88 |
抗菌胜肽(Antimicrobial peptide)、多黏菌素B(Polymyxin B)、革蘭氏陰性菌(Gram-negative bacteria)、抗藥性(Drug resistance) 抗菌胜肽(... | ||||
| 105 | 抗菌胜肽與... 抗菌胜肽與抗生素合併使用對於多重抗藥性臨床菌株之協同功效研究 (Synergistic effects of ultrashort antimicrobial peptides and antibiotics against multi-drug resistant clinical bacteria) | NTHU NDLTD | 碩 | 1.88 |
抗菌胜肽(antimicrobial peptide)、協同功效(combination effect)、多重抗藥性(multi-drug resistant)、萬古黴素(vancomycin) 抗菌胜肽(... | ||||
| 105 | 新型CXC... 新型CXC-受體拮抗劑(pT12S)之抗癌效果研究 (A novel CXCR1/2 antagonist (pT12S) as a potent anticancer drug) | NTHU NDLTD | 碩 | 1.88 |
介白素-8(Interleukin-8 (IL-8))、CXC-受體 (CXCR1/2)(CXCR1/2)、拮抗劑(antagonist)、抗癌胜肽(anticancer peptide)、EGFR-TKI(EGFR-TKI)、EGFR-TKI抗藥性(EGFR-TKI resistance)、化療抗藥性(chemoresistance)、非小細胞肺癌(NSCLC) 介白素-8... | ||||
| 104 | 以非天然巨... 以非天然巨大胺基酸提升末端疏水性抗菌胜肽與脂多醣於水溶液中結構之抗內毒素機制探討 (Solution structure of the antimicrobial peptide with non-nature bulky amino acid end-tags in lipopolysaccharide micelles outlines the mechanism of antiendotoxin activities) | NTHU NDLTD | 碩(提早入學) | 暫無口試日期 |
抗菌胜肽(Antimicrobial peptide)、脂多醣(Lipopolysaccharide) 抗菌胜肽(... | ||||
| 103 | 非自然胺基... 非自然胺基酸置換之抗菌胜肽P-113對於中和內毒素效益之探討 (Correlations Between Bulky Non-natural Amino Acid Substitution and Anti-endotoxin Activity in the Antimicrobial Peptide P-113) | NTHU NDLTD | 碩 | 暫無口試日期 |
抗菌蛋白(Antimicrobial peptide)、抗內毒素(Anti-endotoxin)、脂多糖(Lipopolysaccharide)、非自然胺基酸(Non-natural Amino Acid) 抗菌蛋白(... | ||||
| 103 | ELR-C... ELR-CXC趨化素受體的拮抗劑之設計與特性分析 (Design and characterization of an ELR-CXC chemokine receptor antagonist) | NTHU NDLTD | 碩 | 暫無口試日期 |
介白素 8(IL-8)、受體 CXCR1/2(CXCR1/2)、ELR-CXC 趨化素(CXC chemokine)、發炎(Inflammation) 介白素 8... | ||||
| 102 | 抗菌胜肽之... 抗菌胜肽之設計, 物性描述與分子動力模擬 (Design, Characterization, and Molecular Dynamics Simulations of Antimicrobial Peptides) | NTHU NDLTD | 碩 | 暫無口試日期 |
分子動力模擬(Molecular Dynamics Simulations) 分子動力模... | ||||
| 102 | 極短鏈抗菌... 極短鏈抗菌胜肽中和內毒素效益之機制探討 (Unravel the Mechanism of Endotoxin Neutralization Effect of Ultra-short Antimicrobial Peptides) | NTHU NDLTD | 碩 | 暫無口試日期 |
脂多糖(Lipopolysaccharide)、敗血症(sepsis)、極短鏈的抗菌胜肽(ultra-short antimicrobial peptide) 脂多糖(L... | ||||
| 102 | 由分子動力... 由分子動力模擬設計抗菌及抗癌胜肽之研究 (From Molecular Dynamic simulation to antimicrobial and anticancer peptide design) | NTHU NDLTD | 碩 | 暫無口試日期 |
抗菌胜肽(Antimicrobial peptide)、抗癌胜肽(Anticancer peptide)、分子動力模擬(Molecular Dynamic simulation) 抗菌胜肽(... | ||||
| 101 | 顯著增加短... 顯著增加短鏈抗菌肽抗內毒素之效益 (Boosting Anti-Endotoxin Effects of short Antimicrobial Peptides) | NTHU NDLTD | 碩 | 暫無口試日期 |
抗內毒素(anti-endotoxin effect)、萘基丙胺酸(β-naphthylalanine)、尾端修飾(end-tagging)、短鏈抗菌肽(short antimicroial peptides) 抗內毒素(... |