政府計畫(GRB),建議「依年度遞減排序」,以查看最新的研究方向。
畢業學年度 | 論文標題 | 連結 | 學位 | 畢業時長(years) |
---|---|---|---|---|
關鍵字 | ||||
111 | Dieff... Dieffenbachia standleyi和Rhaphidophora megaphylla的水層萃取物可促進受損腦神經元的神經軸再生並改善腦傷小鼠的運動功能 (The aqueous fractions of Dieffenbachia standleyi and Rhaphidophora megaphylla promote neurite re-growth of injured brain neurons and improve motor function recovery of controlled cortical impact mice) | NTHU NDLTD | 碩 | 1.98 |
植物萃取物(Plant extracts)、中樞神經再生(CNS regeneration)、腦神經再生(Cranial Nerve Regeneration)、動物行為實驗(Animal behavior experiments)、初代神經元培養(Primary neuron culture) 植物萃取物... | ||||
111 | 促進神經軸... 促進神經軸再生的小分子化合物NRC-3及其衍生物之合成研究 (Synthesis of NRC-3 and its derivatives for promoting neurite re-growth) | NTHU NDLTD | 碩 | 0.98 |
小分子化合物(small molecular compound)、全合成(total synthesis)、創傷性腦損傷(traumatic brain injury) 小分子化合... | ||||
111 | PGAM5... PGAM5適時的表現量與剪切調控創傷性腦損傷後的粒線體恆定、神經突再生與功能恢復 (Timely expression and cleavage of PGAM5 regulate mitochondrial homeostasis, neurite re-growth and functional recovery after traumatic brain injury) | NTHU NDLTD | 碩逕博 | 5.93 |
創傷性腦損傷(traumatic brain injury)、PGAM5蛋白(PGAM5)、粒線體恆定(mitochondrial homeostasis)、神經突再生(neurite re-growth)、功能恢復(functional recovery)、表觀遺傳學(epigenetics) 創傷性腦損... | ||||
111 | Wnt拮抗... Wnt拮抗作用透過增強細胞黏著連接及限縮分化方向促進間質幹細胞快速軟骨分化 (Wnt Antagonism without TGFβ Induces Rapid MSC Chondrogenesis via Increasing AJ Interactions and Restricting Lineage Commitment) | NTHU NDLTD | 博 | 7.45 |
人類間質幹細胞(Human mesenchymal stem cells (hMSCs))、誘導性多能幹細胞(induced pluripotent stem cells (iPSCs))、軟骨分化(chondrogenic differentiation)、Wnt/β-catenin訊息傳遞路徑(Wnt/β-catenin signaling)、細胞黏著連接(adherens junction)、N-鈣黏蛋白(N-cadherin) 人類間質幹... | ||||
110 | Wnt8a... Wnt8a 基因在神經元再生過程中通過啟動子及增強子相互作用的調控機制 (The regulatory mechanism of Wnt8a transcription via promoter-enhancer interaction during neurite re-growth) | NTHU NDLTD | 碩 | 1.99 |
神經軸生長(epigenetics)、增強子(Wnt8a)、表觀遺傳學(enhancer)、腦傷(neurite regrowth) 神經軸生長... | ||||
110 | WNT3A... WNT3A-TCF4促進皮質神經再生過程中Nfe2l2基因的表現 (WNT3A-TCF4 mediates transcriptional activation of Nfe2l2 during re-growth of injured cortical neurons) | NTHU NDLTD | 碩 | 0.99 |
創傷性腦損傷(epigenetics)、神經軸生長(neurite re-growth)、表觀遺傳學(traumatic brain injury) 創傷性腦損... | ||||
110 | 藉由台灣人... 藉由台灣人體生物資料庫及國外癌症資料庫研究頭頸癌與憂鬱症的可能生物標記物 (Identify DNA methylation potential biomarkers for head and neck squamous cell carcinoma and depression by approaching Taiwan Biobank and foreign cancer database) | NTHU NDLTD | 碩 | 0.99 |
酒精攝取(alcohol consumption)、DNA甲基化(DNA methylation)、頭頸癌(HNSCC)、憂鬱症(depression)、臺灣人體生物資料庫(Taiwan Biobank)、TCGA資料庫(TCGA database)、GEO資料庫(GEO database)、生物標記物(biomarker) 酒精攝取(... | ||||
110 | ASCL1... ASCL1的高表現抑制受損皮質和海馬迴神經的突觸再生並促進星狀膠質細胞轉化成神經細胞 (High ASCL1 expression inhibits neurite re-growth of injured cortical and hippocampal neurons and promotes astrocyte-to-neuron conversion) | NTHU NDLTD | 碩 | 0.99 |
神經軸再生(neurite re-growth)、神經新生(CNS)、中樞神經系統(astrocyte-to-neuron conversion)、星狀膠質細胞(HES5)、創傷性腦損傷(ASCL1) 神經軸再生... | ||||
110 | 皮質神經再... 皮質神經再生過程中調控WNT3A基因轉錄的啟動子及增強子立體作用 (Genome organization of enhancer-promoter interaction toward WNT3A transcription during regeneration of injured cortical neurons) | NTHU NDLTD | 碩 | 1.28 |
神經再生(neuron regeneration)、基因調控(gene regulation)、增強子(enhancer)、WNT3A基因(WNT3A)、染色體構象捕獲(chromatin conformation capture (3C)) 神經再生(... | ||||
110 | 橫紋肌肉瘤... 橫紋肌肉瘤細胞中PTPRN2的高表現量影響肌動蛋白解聚合和肌母細胞融合缺陷 (Increased PTPRN2 in rhabdomyosarcoma cells contributes to actin depolymerization and fusion defect of myoblasts) | NTHU NDLTD | 碩 | 2.12 |
橫紋肌肉瘤(rhabdomyosarcoma)、DNA甲基化(DNA methylation)、成肌過程(myogenesis)、肌動蛋白(actin)、磷脂質(phopholipid)、磷酯肌醇二磷酸(phosphatidylinositol-4,5-bisphosphate) 橫紋肌肉瘤... | ||||
109 | 嗎啡成癮減... 嗎啡成癮減少粒線體β-氧化相關基因表現並促進乳癌的增生和轉移 (Morphine addiction reduces expression of mitochondrial β-oxidation related genes and promotes proliferation and metastasis of breast cancer cells) | NTHU NDLTD | 碩 | 2.08 |
嗎啡成癮(Morphineaddiction)、粒線體β-氧化(mitochondrialβ-oxidation)、乳癌增生(breastcancerproliferation)、乳癌轉移(breastcancermetastasis) 嗎啡成癮(... | ||||
108 | 篩選可在創... 篩選可在創傷性腦損傷後促進腦神經再生的植物萃取物 (Screening of plant extracts that promote neuronal regeneration upon traumatic brain injury) | NTHU NDLTD | 碩 | 0.99 |
創傷性腦損傷(traumatic brain injury)、神經再生(neuronal regeneration)、植物萃取物(plant extract) 創傷性腦損... | ||||
108 | 鼻腔給予W... 鼻腔給予WNT3A蛋白促進創傷性腦損傷後的大腦功能恢復 (Intranasal administration of WNT3A improves functional recovery after traumatic brain injury) | NTHU NDLTD | 碩 | 0.99 |
創傷性腦損傷(Traumatic brain injury)、神經再生(Neuronal regeneration)、鼻腔給藥(WNT3A)、行為實驗(Intranasal administration) 創傷性腦損... | ||||
108 | 源自間質性... 源自間質性幹細胞及皮質神經細胞的粒線體促進受損的海馬迴神經再生 (Transplantation of mitochondria derived from mesenchymal stem cells and cortical neurons promotes neurite re-growth of injured hippocampal neurons) | NTHU NDLTD | 碩 | 0.99 |
粒線體(mitochondria)、粒線體移植(mitochonddria transplantation)、間質性幹細胞(mesenchymal stem cell)、皮質神經細胞(cortical neuron)、海馬迴神經再生(hippocampal neuron) 粒線體(m... | ||||
108 | 醌類分子I... 醌類分子Isoplumbagin藉由標靶NQO1蛋白並降低粒線體功能抑制口腔鱗狀上皮細胞癌生長及轉移 (Isoplumbagin directly targets NQO1 to reduce mitochondrial function in oral squamous cells carcinoma) | NTHU NDLTD | 碩 | 1.96 |
異白花丹素(isoplumbagin)、菸草醯胺腺嘌呤二核苷酸磷酸鹽-醌去氫酶1(NQO1)、醌類分子(quinone)、口腔鱗狀細胞癌(oral squamous cells carcinoma)、轉移(metastasis)、粒線體(mitochondria) 異白花丹素... | ||||
108 | 促進皮質神... 促進皮質神經再生過程中的WNT3A基因增強子表觀遺傳修飾及KLF4的抑制效果 (Epigenetic regulation of enhancer for induced WNT3A and inhibitory effect of KLF4 during regeneration of injured cortical neurons) | NTHU NDLTD | 碩逕博 | 6.50 |
皮質神經細胞元(neuronal regeneration)、創傷性腦損傷(traumatic brain injury)、增強子(WNT3A)、組蛋白修飾(enhancer regulation)、WNT3A蛋白(histone modification)、KLF4轉錄因子(cortical neurons)、神經再生(klf4) 皮質神經細... | ||||
108 | Hes5抑... Hes5抑制皮質神經細胞生長及再生 (Hes5 inhibits neurite outgrowth and re-growth of cortical neurons) | NTHU NDLTD | 碩 | 2.34 |
Hes5(Hes5)、抑制(inhibits)、皮質神經細胞(neurite)、生長(outgrowth)、再生(re-growth) Hes5(... | ||||
108 | 皮質神經元... 皮質神經元再生過程中WNT3A上游增強子核糖核酸表達的分析 (Analysis of WNT3A upstream enhancer RNA expression during regeneration of cortical neurons) | NTHU NDLTD | 碩(外籍生) | 1.05 |
皮質神經元(WNT3A)、再生(enhancer)、增強子(neuron)、核糖核酸(undefined) 皮質神經元... | ||||
107 | K他命成癮... K他命成癮增加BMP5、EGFR和WNT5A基因表現並促進乳癌的轉移 (Ketamine addiction increases expression of BMP5, EGFR and WNT5A genes and promotes metastasis of breast cancer) | NTHU NDLTD | 碩 | 1.91 |
K他命(Ketamine)、嗎啡(Morphine)、乳癌(breast cancer)、腫瘤微環境(BMP5)、骨形態發生蛋白(EGFR)、表皮生長因子受體(WNT5A) K他命(K... | ||||
107 | 探討曲古抑... 探討曲古抑菌素及漆樹酸在神經再生中的效果 (Investigate the effects of Trichostatin A and Anacardic Acid during neuronal regeneration) | NTHU NDLTD | 碩 | 4.79 |
神經再生(Neuronal regeneration)、曲古抑菌素(Trichostatin A (TSA))、漆樹酸(Anacardic acid (AA))、組蛋白脫乙醯酶(Histone deacetylases (HDACs))、組蛋白乙醯轉移酶(Histone acetyltransferases (HATs)) 神經再生(... | ||||
107 | 14-3-... 14-3-3 β、ε及γ異構體調節肌肉分化 (14-3-3 β, ε, and γ isoforms regulate myogenesis) | NTHU NDLTD | 碩 | 4.16 |
C2C12細胞株(C2C12)、肌肉分化(myogenesis)、14-3-3異構體(14-3-3 isoform) C2C12... | ||||
106 | 探討14-... 探討14-3-3ε調控第一型金屬硫蛋白Metallothionein-1 在肝癌腫瘤進展中所扮演之角色 (The Roles of 14-3-3ε-regulated Metallothionein-1 in Tumor Progression of Hepatocellular Carcinoma) | NTHU NDLTD | 博 | 6.88 |
肝細胞癌(14-3-3ε)、第一型金屬硫蛋白(AKR1B10)、醛酮還原酶家族(Metallothionein-1)、吡咯烷二硫代氨基甲(PDTC)、表觀遺傳(ZNF479) 肝細胞癌(... | ||||
106 | 長的非編碼... 長的非編碼核糖核酸AABR07056156.1 (Lnc156) 促進皮質神經細胞的再生 (Long non-coding RNA AABR07056156.1 (Lnc156) promotes regeneration of cortical neurons) | NTHU NDLTD | 碩 | 2.49 |
再生(regeneration)、長的非編碼核醣核酸(long non-coding RNA)、中樞神經(central nervous system)、皮質神經細胞(cortical neurons) 再生(re... | ||||
106 | 肌肉發育過... 肌肉發育過程中磷脂質參與肌原母細胞之融合 (Phospholipids participate in the myoblast fusion during myogenesis) | NTHU NDLTD | 碩 | 1.48 |
肌肉發育(myogenesis)、肌肉(myoblast)、肌原母細胞(muscle)、細胞膜突出(bleb)、磷脂質(phopholipid) 肌肉發育(... | ||||
106 | 致癌基因 ... 致癌基因 ROS1 上升促進口腔癌轉移 (Upregulation of ROS1 oncogene promotes oral cancer metastasis) | NTHU NDLTD | 博 | 5.23 |
致癌基因(oncogene)、口腔癌(oral cancer)、轉移(metastasis)、表皮生長因子受體(epidermal growth factor receptor)、表觀基因調控(epigenetic regulation)、組織蛋白甲基轉移酶(histone methyltransferase) 致癌基因(... | ||||
106 | 粒線體療法... 粒線體療法可促進海馬迴神經細胞的再生 (Mitochondrial therapy promotes regeneration of hippocampal neurons) | NTHU NDLTD | 碩 | 2.19 |
中樞神經再生(Neuronal regeneration)、粒線體(Mitochondrial therapy) 中樞神經再... | ||||
105 | MiR-2... MiR-200a-3p 在口腔癌細胞侵襲過程中對 EZH2 的後轉錄調控 (The post-transcriptional regulation of EZH2 by miR-200a-3p during oral cancer cell invasion) | NTHU NDLTD | 碩 | 1.97 |
口腔癌(EZH2)、組蛋白甲基轉移酶(miRNA)、小分子核糖核酸(miR-200a-3p) 口腔癌(E... | ||||
105 | 二甲基甘胺... 二甲基甘胺酸改善甲苯暴露所誘發之行為異常 (N,N-dimethylglycine Ameliorates Behavioral Disturbances Induced by Toluene Exposure) | NTHU NDLTD | 碩 | 1.92 |
甲苯(toluene)、二甲基甘胺酸(dimethylglycine) 甲苯(to... | ||||
105 | 娃兒藤生物... 娃兒藤生物鹼在脂多醣及干擾素伽瑪活化之巨噬細胞內抗發炎之直接標靶及其相關訊息傳遞路徑之研究 (Study on the direct targets of tylophorine and its associated effective pathways in LPS/IFN-gamma stimulated Raw264.7 cells) | NTHU NDLTD | 碩 | 2.64 |
娃兒藤生物鹼(tylophorine)、瓦氏效應(warburg effect) 娃兒藤生物... | ||||
104 | 探討COM... 探討COMMD1經由微核糖核酸205的負向調控以形成癌細胞內擴大發炎和幹性屬性的正向循環機制 (Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells) | NTHU NDLTD | 博 | 暫無口試日期 |
發炎(inflammation)、癌幹細胞(cancer stem cell)、微核醣核酸205(microRNA-205) 發炎(in... | ||||
104 | 確認在神經... 確認在神經再生當中KLF7的標的基因 (Identification of KLF7 target genes during neuronal regeneration) | NTHU NDLTD | 碩 | 暫無口試日期 |
神經再生(neuronal regeneretion) 神經再生(... | ||||
104 | STAT3... STAT3調控EZH2表現進而影響口腔癌的轉移 (STAT3-mediated EZH2 expression modulates migration and invasion of oral cancer) | NTHU NDLTD | 碩 | 暫無口試日期 |
口腔癌(EZH2)、轉移(oral cancer) 口腔癌(E... | ||||
104 | WNT3A... WNT3A可藉由增加BDNF, KLF7以及GAP43的表現量來促進皮質神經細胞的再生 (WNT3A promotes regeneration of cortical neurons in part through increasing expression of BDNF, KLF7 and GAP43) | NTHU NDLTD | 碩 | 暫無口試日期 |
皮質神經細胞再生(regeneration of cortical neurons) 皮質神經細... | ||||
103 | 建構基因表... 建構基因表達載體以觀察形成長期記憶神經元的基因調控 (Developing promoter-driven constructs for visualizing neural activity) | NTHU NDLTD | 碩 | 暫無口試日期 |
長期記憶(Drosophila)、果蠅(long term memory)、啟動子(promoter)、血清素受體(CREB) 長期記憶(... | ||||
102 | 在飲食限制... 在飲食限制或高油脂飲食的條件下纖維母細胞生長因子第一型在小鼠腦內的表現 (Spatial expression of FGF1 in the mouse brain under the condition of food restriction or high-fat diet) | NTHU NDLTD | 碩 | 暫無口試日期 |
纖維母細胞生長因子第一型(FGF1)(FGF1)、腦室旁神經核(PVN)(PVN)、oxytocin(oxytocin)、nesfatin-1(nesfatin-1)、飲食調控(diet regulation) 纖維母細胞... | ||||
102 | EZH2抑... EZH2抑制口腔癌細胞侵襲性之新發現 (The novel role of EZH2 in inhibiting invasion of oral cancer cells) | NTHU NDLTD | 碩 | 暫無口試日期 |
口腔癌(Oral cancer)、細胞侵襲(Cell invasion) 口腔癌(O... | ||||
102 | 低劑量游離... 低劑量游離輻射促進海馬迴神經細胞中粒線體的融合 (Low dose ionizing radiation promotes mitochondrial fusion in hippocampal neurons) | NTHU NDLTD | 碩 | 暫無口試日期 |
放射線(radiation)、低劑量(low dose radiation)、粒線體(mitochondria)、粒線體融合(fusion)、海馬迴神經細胞(hippocampal neuron)、乙型-澱粉樣蛋白(beta-amyloid) 放射線(r... | ||||
102 | 使用微陣列... 使用微陣列西方分析法分析正常與惡性前列腺細胞系之間的表達差異 (Profiling the protein expression difference between normal vs. malignant prostate cell lines using Micro-Western Array) | NTHU NDLTD | 碩 | 暫無口試日期 |
前列腺癌(prostate cancer) 前列腺癌(... | ||||
101 | 探討 IR... 探討 IRSp53 和 SH2B1beta 在形成絲狀偽足中的角色 (Role of IRSp53 and SH2B1beta in filopodium formation) | NTHU NDLTD | 碩 | 暫無口試日期 |
絲狀偽足(IRSp53) 絲狀偽足(... | ||||
101 | 探討 in... 探討 interleukin-8 促進口腔癌細胞增生能力的機制 (Investigate how interleukin-8 promotes oral cancer cell proliferation) | NTHU NDLTD | 碩 | 暫無口試日期 |
口腔癌(Oral cancer)、IL-8(IL-8)、PI3K-AKT 路徑(PI3K-AKT pathway)、MEK-ERK1/2 路徑(MEK-ERK1/2 pathway) 口腔癌(O... | ||||
101 | 探討口腔癌... 探討口腔癌細胞增生及移動的調控機制 (Regulation of oral cancer cell proliferation and migration) | NTHU NDLTD | 碩 | 暫無口試日期 |
口腔癌、細胞增生、訊息傳遞機制 口腔癌、細... | ||||
101 | 非受體型特... 非受體型特異性酪胺酸去磷酸酶23在上皮生長因子受體訊息傳遞之調控角色探討 (The regulatory role of PTPN23 on EGFR signaling) | NTHU NDLTD | 碩 | 暫無口試日期 |
肺癌(Lung cancer)、受體型酪胺酸磷酸酶(PTPN23)、表皮生長因子受體(EGFR)、腫瘤壞死因子受體(TNFR)、細胞凋亡(Apoptosis) 肺癌(Lu... |